Scleroderma is a rare connective tissue disease that is manifested by cutaneous sclerosis
and variable systemic involvement. Two categories of scleroderma are known: systemic …

Background: Scleroderma is a chronic connective tissue disease that results in fibrosis of the
skin and internal organs. Although internal organ involvement corresponds with poor …

The term 'sclerosing diseases of the skin'comprises specific dermatological entities, which
have fibrotic changes of the skin in common. These diseases mostly manifest in different …

Localized scleroderma designates a heterogeneous group of sclerotic skin disorders.
Depending on the subtype, severity, and site affected, adjacent structures such as adipose …

Objective Juvenile localized scleroderma (LS) is a chronic inflammatory skin disorder
associated with substantial morbidity and disability. Although a wide range of therapeutic …

Scleroderma is a disorder involving oral and facial tissues, with skin hardening, thin lips,
deep wrinkles, xerostomia, tongue rigidity, and microstomia. The aim of this study was to …

Summary Background Systemic sclerosis (SSc) and morphoea are connective tissue
diseases characterized by fibrosis of the skin. Although to date their pathogenesis has not …

Abstract Purpose of Review First recognized in 1974, eosinophilic fasciitis (EF) is a fibrosing
disorder of the fascia with characteristic cutaneous and hematologic manifestations. This …

Morphea or localized scleroderma is a distinctive inflammatory disease that leads to
sclerosis of the skin and subcutaneous tissues. It comprises a number of subtypes …

We established diagnostic criteria and severity classification of localized scleroderma
because there is no established diagnostic criteria or widely accepted severity classification …