BACKGROUND Although laboratory procedures, along with culture media formulations,
have improved over the past two decades, the issue remains that human IVF is performed in …

Oocytes and preimplantation embryos require careful regulation of the redox environment
for optimal development both in vivo and in vitro. Reactive oxygen species (ROS) are …

In brief Reactive oxygen species are generated throughout the pre-implantation period and
are necessary for normal embryo formation. However, at pathological levels, they result in …

Many factors affect development of mammalian preimplantation embryos in vitro. It is well
known that in vitro development of bovine embryos is highly affected by culture condition …

A major obstacel to the study of mammalian development, and to the practical application of
knowledge gained from it in the clinic during therapeutic in vitro fertilisation and embryo …

OBJECTIVE: To assess the total antioxidant potential of women with endometriosis-
associated infertility, women with idiopathic infertility, and fertile controls. DESIGN …

Glutathione (GSH) is a major source of reducing equivalents in mammalian cells. To
examine the role of GSH synthesis in development and cell growth, we generated mice …

In vitro maturation (IVM) is emerging as a popular technology at the forefront of fertility
treatment and preservation. However, standard in vitro culture (IVC) conditions usually …

The mRNA expression of five enzymes: catalase, Cu-Zn-superoxide dismutase (Cu-Zn-
SOD), Mn-superoxide dismutase (Mn-SOD), glutathione peroxidase (GPX), and γ …

Recent progress, briefly reviewed here, has led to utility of bovine in vitro oocyte maturation
(IVM), in vitro fertilization (IVF), embryo culture and embryo transfer (ET) technologies in …