[HTML][HTML] Osteoporosis pathogenesis and treatment: existing and emerging avenues

B Liang, G Burley, S Lin, YC Shi - Cellular & Molecular Biology Letters, 2022 - Springer
Osteoporotic fractures lead to increased disability and mortality in the elderly population.
With the rapid increase in the aging population around the globe, more effective treatments …

[HTML][HTML] Clinical application of bone marrow mesenchymal stem/stromal cells to repair skeletal tissue

A Arthur, S Gronthos - International journal of molecular sciences, 2020 - mdpi.com
There has been an escalation in reports over the last decade examining the efficacy of bone
marrow derived mesenchymal stem/stromal cells (BMSC) in bone tissue engineering and …

[HTML][HTML] Therapeutic potential of mesenchymal stem cells for cancer therapy

A Hmadcha, A Martin-Montalvo, BR Gauthier… - … in bioengineering and …, 2020 - frontiersin.org
Mesenchymal stem cells (MSCs) are among the most frequently used cell type for
regenerative medicine. A large number of studies have shown the beneficial effects of MSC …

Clinical trials with mesenchymal stem cells: an update

T Squillaro, G Peluso, U Galderisi - Cell transplantation, 2016 - journals.sagepub.com
In the last year, the promising features of mesenchymal stem cells (MSCs), including their
regenerative properties and ability to differentiate into diverse cell lineages, have generated …

Management of endocrine disease: Osteogenesis imperfecta: An update on clinical features and therapies

R Marom, BM Rabenhorst… - European journal of …, 2020 - academic.oup.com
Osteogenesis imperfecta (OI) is an inherited skeletal dysplasia characterized by bone
fragility and skeletal deformities. While the majority of cases are associated with pathogenic …

[HTML][HTML] Immune modulation by transplanted calcium phosphate biomaterials and human mesenchymal stromal cells in bone regeneration

P Humbert, MÁ Brennan, N Davison, P Rosset… - Frontiers in …, 2019 - frontiersin.org
A wide variety of biomaterials have been developed as both stabilizing structures for the
injured bone and inducers of bone neoformation. They differ in chemical composition …

[HTML][HTML] Mesenchymal stromal cells and exosomes: progress and challenges

MH Forsberg, JA Kink, P Hematti… - Frontiers in cell and …, 2020 - frontiersin.org
Due to their robust immunomodulatory capabilities, mesenchymal stem/stromal cells (MSCs)
have been used as a cellular therapy for a number of human diseases. Part of the …

Osteogenesis imperfecta and therapeutics

R Morello - Matrix Biology, 2018 - Elsevier
Osteogenesis imperfecta, or brittle bone disease, is a congenital disease that primarily
causes low bone mass and bone fractures but it can negatively affect other organs. It is …

[HTML][HTML] Osteogenesis imperfecta: current and prospective therapies

M Botor, A Fus-Kujawa, M Uroczynska, KL Stepien… - Biomolecules, 2021 - mdpi.com
Osteogenesis Imperfecta (OI) is a group of connective tissue disorders with a broad range of
phenotypes characterized primarily by bone fragility. The prevalence of OI ranges from …

[HTML][HTML] Current overview of osteogenesis imperfecta

M Deguchi, S Tsuji, D Katsura, K Kasahara, F Kimura… - Medicina, 2021 - mdpi.com
Osteogenesis imperfecta (OI), or brittle bone disease, is a heterogeneous disorder
characterised by bone fragility, multiple fractures, bone deformity, and short stature. OI is a …