Porphyromonas gingivalis, a gram-negative anaerobe, is a major etiological agent in the
initiation and progression of severe forms of periodontal disease. An opportunistic pathogen …

Discusses the role of bacterial proteinases in matrix destruction and modulation of host
responses. Evasion of host defense mechanisms; Mechanism of gingipain inference with …

Seymour et Al. hanno proposto un modello di immunopatogenesi secondo cui i soggetti
suscettibili alla malattia parodontale possono avere un incremento di cellule T Helper 2, che …

Gingipains, extracellular cysteine proteinases of Porphyromonas gingivalis, constitute the
major virulence factor of this periodontopathogenic bacterium. They are the product of three …

Porphyromonas gingivalis produces arginine-specific cysteine proteinase (Arg-gingipain,
RGP) and lysine-specific cysteine proteinase (Lys-gingipain, KGP) in the extracellular and …

The gingipains are cell surface Arg-and Lys-specific proteinases of the bacterium
Porphyromons gingivalis, which has been associated with periodontitis, a disease that …

The cysteine proteases of Porphyromonas gingivalis are extracellular products of an
important etiological agent in periodontal diseases. Many of the in vitro actions of these …

Porphyromonas gingivalis has been implicated as an etiologic agent of adult periodontitis.
We have previously shown that P. gingivalis can degrade the epithelial cell-cell junction …

Porphyromonas gingivalis is one of the principal organisms associated with adult
periodontitis. Bacterial surface proteins such as fimbriae and gingipain hemagglutinin …

Proteases of Porphyromonas gingivalis are considered to be important virulence
determinants of this periodontal bacterium. Several biochemical isoforms of arginine-specific …