[HTML][HTML] Luteolin as a potential hepatoprotective drug: Molecular mechanisms and treatment strategies

C Yao, S Dai, C Wang, K Fu, R Wu, X Zhao… - Biomedicine & …, 2023 - Elsevier
Luteolin is a flavonoid widely present in various traditional Chinese medicines. In recent
years, luteolin has received more attention due to its impressive liver protective effect, such …

Progress in the treatment of drug-induced liver injury with natural products

Y Sun, Y Zhang, L Xie, F Rong, X Zhu, J Xie… - Pharmacological …, 2022 - Elsevier
There are numerous prescription drugs and non-prescription drugs that cause drug-induced
liver injury (DILI), which is the main cause of liver disease in humans around the globe. Its …

Luteolin: A flavone with myriads of bioactivities and food applications

SP Bangar, P Kajla, V Chaudhary, N Sharma, F Ozogul - Food Bioscience, 2023 - Elsevier
Flavonoids are increasingly applied in foods to promote their functional properties, human
health, and overall wellbeing. Luteolin, a polyphenolic plant flavonoid, is recognized as one …

Paeoniflorin ameliorates lipopolysaccharide‐induced acute liver injury by inhibiting oxidative stress and inflammation via SIRT1/FOXO1a/SOD2 signaling in rats

L Li, H Wang, S Zhao, Y Zhao, Y Chen… - Phytotherapy …, 2022 - Wiley Online Library
Acute liver injury (ALI) is a poor prognosis and high mortality complication of sepsis.
Paeoniflorin (PF) has remarkable anti‐inflammatory effects in different disease models …

Human diet‐derived polyphenolic compounds and hepatic diseases: From therapeutic mechanisms to clinical utilization

Q Hu, W Zhang, F Wei, M Huang, M Shu… - Phytotherapy …, 2024 - Wiley Online Library
This review focuses on the potential ameliorative effects of polyphenolic compounds derived
from human diet on hepatic diseases. It discusses the molecular mechanisms and recent …

Active Flavonoids From Lagotis brachystachya Attenuate Monosodium Urate-Induced Gouty Arthritis via Inhibiting TLR4/MyD88/NF-κB Pathway and NLRP3 …

X Ouyang, NZ Li, MX Guo, MM Zhang… - Frontiers in …, 2021 - frontiersin.org
Lagotis brachystachya Maxim is a characteristic herb commonly used in Tibetan medicine.
Tibetan medicine records it as an important medicine for the clinical treatment of “Yellow …

Effects of luteolin on sepsis: a comprehensive systematic review

M Vajdi, A Karimi, M Karimi, MA Farhangi, G Askari - Phytomedicine, 2023 - Elsevier
Background Sepsis and septic shock are the main causes of mortality and complications in
intensive care units all over the world. Luteolin is thought to have a significant role as a free …

N-trimethyl chitosan coated targeting nanoparticles improve the oral bioavailability and antioxidant activity of vitexin

S Li, H Lv, Y Chen, H Song, Y Zhang, S Wang… - Carbohydrate …, 2022 - Elsevier
Vitexin is a flavonoid which exerted many protective activities. However, the low
bioavailability discounts the in vivo effects of vitexin. This study designed vitexin loaded …

Recent advances in the effects of dietary polyphenols on inflammation in vivo: Potential molecular mechanisms, receptor targets, safety issues, and uses of …

D Wang, T Wang, Z Zhang, Z Li, Y Guo, G Zhao… - Current Opinion in Food …, 2022 - Elsevier
High dietary intake of dietary polyphenols is associated with a decreased risk of chronic
diseases, especially in inflammation. However, mechanisms responsible for their anti …

Retinoic acid protects against lipopolysaccharide-induced ferroptotic liver injury and iron disorders by regulating Nrf2/HO-1 and RARβ signaling

X Lai, A Wu, Y Bing, Y Liu, J Luo, H Yan… - Free Radical Biology …, 2023 - Elsevier
Acute liver injury (ALI) can progress to severe liver diseases, making its prevention and
treatment a focus of research. Retinoic acid (RA) has been shown to have anti-oxidative and …