Physiological imaging of the lung: single-photon-emission computed tomography (SPECT)

J Petersson, A Sánchez-Crespo… - Journal of applied …, 2007 - journals.physiology.org
Emission tomography provides three-dimensional, quantitative images of the distribution of
radiotracers used to mark physiological, metabolic, or pathological processes. Quantitative …

Visualizing lung function with positron emission tomography

RS Harris, DP Schuster - Journal of applied physiology, 2007 - journals.physiology.org
Positron emission tomography (PET) provides three-dimensional images of the distributions
of radionuclides that have been inhaled or injected into the lungs. By using radionuclides …

Topographical distribution of pulmonary perfusion and ventilation, assessed by PET in supine and prone humans

G Musch, JDH Layfield, RS Harris… - Journal of applied …, 2002 - journals.physiology.org
Using positron emission tomography (PET) and intravenously injected 13N2, we assessed
the topographical distribution of pulmonary perfusion (Q˙) and ventilation (V˙) in six healthy …

Quantification of regional ventilation-perfusion ratios with PET

MFV Melo, D Layfield, RS Harris, K O'neill… - Journal of Nuclear …, 2003 - Soc Nuclear Med
The topographic matching of alveolar ventilation (V̇ A) and perfusion (Q̇) is the main
determinant of gas exchange efficiency of the lung. However, no pulmonary functional …

Quantitative imaging metrics for the assessment of pulmonary pathophysiology: an official American Thoracic Society and Fleischner Society joint workshop report

CCW Hsia, JHT Bates, B Driehuys, SB Fain… - Annals of the …, 2023 - atsjournals.org
Multiple thoracic imaging modalities have been developed to link structure to function in the
diagnosis and monitoring of lung disease. Volumetric computed tomography (CT) renders …

Contributions of pulmonary perfusion and ventilation to heterogeneity in V˙a/Q˙measured by PET

S Treppo, SM Mijailovich… - Journal of Applied …, 1997 - journals.physiology.org
Treppo, Steven, Srboljub M. Mijailovich, and José G. Venegas. Contributions of pulmonary
perfusion and ventilation to heterogeneity in V˙ a/Q˙ measured by PET. J. Appl. Physiol. 82 …

Determination of regional VA/Q by hyperpolarized 3He MRI

RR Rizi, JE Baumgardner, M Ishii… - … in Medicine: An …, 2004 - Wiley Online Library
Alveolar ventilation/perfusion ratio (VA/Q) is a key parameter in functional imaging of the
lung. Herein, regional VA/Q was calculated from regional values of alveolar partial pressure …

[HTML][HTML] Ventilation/perfusion relationships and gas exchange: measurement approaches

SR Hopkins - Comprehensive Physiology, 2020 - ncbi.nlm.nih.gov
Abstract Ventilation-perfusion (VA/Q) matching, the regional matching of the flow of fresh gas
to flow of deoxygenated capillary blood, is the most important mechanism affecting the …

Changes in regional ventilation after autologous blood clot pulmonary embolism

MF Vidal Melo, RS Harris, D Layfield… - The Journal of the …, 2002 - pubs.asahq.org
Background Previous studies have suggested that pulmonary embolism (PE) and
pulmonary artery occlusion result in a shift in alveolar ventilation away from unperfused …

A mathematical model of pulmonary gas exchange under inflammatory stress

A Reynolds, GB Ermentrout, G Clermont - Journal of theoretical biology, 2010 - Elsevier
During a severe local or systemic inflammatory response, immune mediators target lung
tissue. This process may lead to acute lung injury and impaired diffusion of gas molecules …