The Lancet Commission on diabetes: using data to transform diabetes care and patient lives

JCN Chan, LL Lim, NJ Wareham, JE Shaw, TJ Orchard… - The Lancet, 2020 - thelancet.com
Executive summary 2020 will go down in history as the year when the global community was
awakened to the fragility of human health and the interdependence of the ecosystem …

[HTML][HTML] Type 2 diabetes mellitus, oxidative stress and inflammation: examining the links

OO Oguntibeju - International journal of physiology …, 2019 - ncbi.nlm.nih.gov
Diabetes mellitus has been recognised as one of the four major non-communicable
diseases that demands urgent attention from all key shareholders globally in an effort to …

The integrative human microbiome project

HMP Integrative, LM Proctor, HH Creasy… - …, 2019 - ui.adsabs.harvard.edu
Abstract The NIH Human Microbiome Project (HMP) has been carried out over ten years and
two phases to provide resources, methods, and discoveries that link interactions between …

Factors leading to high morbidity and mortality of COVID‐19 in patients with type 2 diabetes

A Rajpal, L Rahimi, F Ismail‐Beigi - Journal of diabetes, 2020 - Wiley Online Library
Abstract Coronavirus disease 2019 (COVID‐19) is a recent pandemic caused by severe
acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2), a novel coronavirus. Diabetes …

[HTML][HTML] Longitudinal multi-omics of host–microbe dynamics in prediabetes

W Zhou, MR Sailani, K Contrepois, Y Zhou, S Ahadi… - Nature, 2019 - nature.com
Type 2 diabetes mellitus (T2D) is a growing health problem, but little is known about its early
disease stages, its effects on biological processes or the transition to clinical T2D. To …

An overview of plant phenolic compounds and their importance in human nutrition and management of type 2 diabetes

D Lin, M Xiao, J Zhao, Z Li, B Xing, X Li, M Kong, L Li… - Molecules, 2016 - mdpi.com
In this paper, the biosynthesis process of phenolic compounds in plants is summarized,
which include the shikimate, pentose phosphate and phenylpropanoid pathways. Plant …

[HTML][HTML] Diabetes mellitus: Classification, mediators, and complications; A gate to identify potential targets for the development of new effective treatments

SA Antar, NA Ashour, M Sharaky, M Khattab… - Biomedicine & …, 2023 - Elsevier
Nowadays, diabetes mellitus has emerged as a significant global public health concern with
a remarkable increase in its prevalence. This review article focuses on the definition of …

CCL2/CCR2 signaling in cancer pathogenesis

Q Hao, JV Vadgama, P Wang - Cell Communication and Signaling, 2020 - Springer
Chemokines are a family of small cytokines, which guide a variety of immune/inflammatory
cells to the site of tumor in tumorigenesis. A dysregulated expression of chemokines is …

Vascular endothelial cells and innate immunity

Y Shao, J Saredy, WY Yang, Y Sun, Y Lu… - … , and vascular biology, 2020 - Am Heart Assoc
In addition to the roles of endothelial cells (ECs) in physiological processes, ECs actively
participate in both innate and adaptive immune responses. We previously reported that, in …

Genome analyses of> 200,000 individuals identify 58 loci for chronic inflammation and highlight pathways that link inflammation and complex disorders

S Ligthart, A Vaez, U Võsa, MG Stathopoulou… - The American Journal of …, 2018 - cell.com
C-reactive protein (CRP) is a sensitive biomarker of chronic low-grade inflammation and is
associated with multiple complex diseases. The genetic determinants of chronic …