Injectable drug delivery systems for osteoarthritis and rheumatoid arthritis

MC Bruno, MC Cristiano, C Celia, N d'Avanzo… - ACS …, 2022 - ACS Publications
Joint diseases are one of the most common causes of morbidity and disability worldwide.
The main diseases that affect joint cartilage are osteoarthritis and rheumatoid arthritis, which …

Polymeric Nanoparticles for Drug Delivery

MA Beach, U Nayanathara, Y Gao, C Zhang… - Chemical …, 2024 - ACS Publications
The recent emergence of nanomedicine has revolutionized the therapeutic landscape and
necessitated the creation of more sophisticated drug delivery systems. Polymeric …

Temperature-responsive multilayer films based on block copolymer-coated silica nanoparticles for long-term release of favipiravir

L Xu, X Zhang, Z Chu, H Wang, Y Li… - ACS Applied Nano …, 2021 - ACS Publications
Using surface-initiated atom-transfer radical polymerization, temperature-responsive block
polymers were functionalized on the surface of silica nanocapsules (SNCs) by a “grafting …

Nanoparticle–cartilage interaction: pathology-based intra-articular drug delivery for osteoarthritis therapy

X Li, B Dai, J Guo, L Zheng, Q Guo, J Peng, J Xu… - Nano-micro letters, 2021 - Springer
Osteoarthritis is the most prevalent chronic and debilitating joint disease, resulting in huge
medical and socioeconomic burdens. Intra-articular administration of agents is clinically …

[HTML][HTML] Intra-articular nanoparticles based therapies for osteoarthritis and rheumatoid arthritis management

J Wen, H Li, H Dai, S Hua, X Long, H Li, S Ivanovski… - Materials Today Bio, 2023 - Elsevier
Osteoarthritis (OA) and rheumatoid arthritis (RA) are chronic and progressive inflammatory
joint diseases that affect a large population worldwide. Intra-articular administration of …

Recent advances in targeted drug delivery for treatment of osteoarthritis

S Mehta, T He, AG Bajpayee - Current opinion in rheumatology, 2021 - journals.lww.com
Recent years have witnessed significant increase in both fundamental and clinical studies
evaluating DDS for osteoarthritis. Steroid encapsulating polymeric microparticles for longer …

Stimulus‐Responsive Drug Delivery Nanoplatforms for Osteoarthritis Therapy

Q Jiang, S Zhang - Small, 2023 - Wiley Online Library
Osteoarthritis (OA) is one of the most prevalent age‐related degenerative diseases. With an
increasingly aging global population, greater numbers of OA patients are providing clear …

Applications and prospects of intra-articular drug delivery system in arthritis therapeutics

P Song, Z Cui, L Hu - Journal of Controlled Release, 2022 - Elsevier
Arthritis is a kind of chronic disease that affects joints and muscles with the symptoms of joint
pain, inflammation and limited movement of joints. Among various clinical therapies, drug …

Stimuli‐Sensitive Nanotherapies for the Treatment of Osteoarthritis

Z Wang, S Wang, K Wang, X Wu… - Macromolecular …, 2021 - Wiley Online Library
Osteoarthritis (OA) is a common chronic inflammatory disease in the joints. It is one of the
leading causes of disability with increasing morbidity, which has become one of the serious …

Polymeric nanoparticles for drug delivery in osteoarthritis

AP Pontes, TJM Welting, J Rip, LB Creemers - Pharmaceutics, 2022 - mdpi.com
Osteoarthritis (OA) is a degenerative musculoskeletal disorder affecting the whole synovial
joint and globally impacts more than one in five individuals aged 40 and over, representing …