Metabolic syndrome: an update on diagnostic criteria, pathogenesis, and genetic links

U Zafar, S Khaliq, HU Ahmad, S Manzoor, KP Lone - Hormones, 2018 - Springer
Metabolic syndrome (MetS), today a major global public health problem, is a cluster of
clinical, metabolic, and biochemical abnormalities, such as central adiposity, hypertension …

[PDF][PDF] Obesity-linked diabetes in the Arab world: a review

B Abuyassin, I Laher - East Mediterr Health J, 2015 - apps.who.int
The Arab world is experiencing an epidemic of obesity and type 2 diabetes mellitus. This
review summarizes the major pathological factors linking obesity to diabetes, focussing on …

[HTML][HTML] Adiponectin GWAS loci harboring extensive allelic heterogeneity exhibit distinct molecular consequences

CN Spracklen, AK Iyengar, S Vadlamudi… - PLoS …, 2020 - journals.plos.org
Loci identified in genome-wide association studies (GWAS) can include multiple distinct
association signals. We sought to identify the molecular basis of multiple association signals …

[HTML][HTML] In silico evaluation of nonsynonymous single nucleotide polymorphisms in the ADIPOQ gene associated with diabetes, obesity, and inflammation

AN Swamy, H Valasala, S Kamma - Avicenna Journal of Medical …, 2015 - ncbi.nlm.nih.gov
Background: The human ADIPOQ gene encodes adiponectin protein hormone, which is
involved in regulating glucose levels as well as fatty acid breakdown. It is exclusively …

Adiponektin vermindert matrizelluläres Remodeling nach kardialer Schädigung durch Hochregulation der Matrix-Metalloproteinase 9-Expression

R Schur - 2019 - refubium.fu-berlin.de
Hintergrund: Adiponektin (APN) ist ein multifunktionelles immunmodulatorisches
Adipozytokin, welches eine durch Druckbelastung und arterielle Hypertension induzierte …

[图书][B] Experimental and computational analysis of the synucleins

A Munyanyi - 2014 - search.proquest.com
The synuclein proteins α, β and γ which are located in the brain, have been a subject of
intense research. Of particular interest is α-synuclein, which is found in misfolded forms in …

Untersuchungen zum funktionellen Einfluss von Einzelnukleotidvariationen in humanen Lipoxygenasen und anderen Genen des LOX-Stoffwechsels

T Horn - 2014 - refubium.fu-berlin.de
Lipoxygenasen (LOXn) bilden eine heterogene Gruppe von Dioxygenasen, die mehrfach
ungesättigte Fettsäuren oxidieren. In epidemiologischen Studien sind eine Reihe von nicht …