Design of liposomes as drug delivery system for therapeutic applications

D Guimarães, A Cavaco-Paulo, E Nogueira - International journal of …, 2021 - Elsevier
Liposomes are spherical vesicles consisting of one or more concentric phospholipid bilayers
enclosing an aqueous core. Being both nontoxic and biodegradable, liposomes represent a …

[HTML][HTML] Liposomes in cancer therapy: how did we start and where are we now

MD Fulton, W Najahi-Missaoui - International Journal of Molecular …, 2023 - mdpi.com
Since their first discovery in the 1960s by Alec Bangham, liposomes have been shown to be
effective drug delivery systems for treating various cancers. Several liposome-based …

[HTML][HTML] Surface functionalization and targeting strategies of liposomes in solid tumor therapy: A review

MK Riaz, MA Riaz, X Zhang, C Lin, KH Wong… - International journal of …, 2018 - mdpi.com
Surface functionalization of liposomes can play a key role in overcoming the current
limitations of nanocarriers to treat solid tumors, ie, biological barriers and physiological …

Biomedical applications of nanotechnology

AP Ramos, MAE Cruz, CB Tovani, P Ciancaglini - Biophysical reviews, 2017 - Springer
The ability to investigate substances at the molecular level has boosted the search for
materials with outstanding properties for use in medicine. The application of these novel …

Gene therapy for drug-resistant glioblastoma via lipid-polymer hybrid nanoparticles combined with focused ultrasound

Q Yang, Y Zhou, J Chen, N Huang… - International journal of …, 2021 - Taylor & Francis
Background Therapy for glioblastoma (GBM) has always been very challenging, not only
because of the presence of the blood-brain barrier (BBB) but also due to susceptibility to …

Recent advances on thermosensitive and pH-sensitive liposomes employed in controlled release

MA Aghdam, R Bagheri, J Mosafer, B Baradaran… - Journal of controlled …, 2019 - Elsevier
Nanotechnology has recently gained lots of interest in drug delivery due to its potential to
improve the therapeutic outcomes of various diseases. Particularly, a wide range of different …

[HTML][HTML] Vitamin C and cardiovascular disease: an update

MB Morelli, J Gambardella, V Castellanos, V Trimarco… - Antioxidants, 2020 - mdpi.com
The potential beneficial effects of the antioxidant properties of vitamin C have been
investigated in a number of pathological conditions. In this review, we assess both clinical …

Precision-guided missile-like DNA nanostructure containing warhead and guidance control for aptamer-based targeted drug delivery into cancer cells in vitro and in …

C Ouyang, S Zhang, C Xue, X Yu, H Xu… - Journal of the …, 2020 - ACS Publications
It is crucial to deliver anticancer drugs to target cells with high precision and efficiency. While
nanomaterials have been shown to enhance the delivery efficiency once they reach the …

DNA logic circuits for cancer theranostics

J Chen, S Fu, C Zhang, H Liu, X Su - Small, 2022 - Wiley Online Library
Cancer diagnosis and therapeutics (theranostics) based on the tumor microenvironment
(TME) and biomarkers has been an emerging approach for precision medicine. DNA …

Lipid-based nanocarriers for oral peptide delivery

Z Niu, I Conejos-Sánchez, BT Griffin… - Advanced drug delivery …, 2016 - Elsevier
This article is aimed to overview the lipid-based nanostructures designed so far for the oral
administration of peptides and proteins, and to analyze the influence of their composition …