[HTML][HTML] EZR promotes pancreatic cancer proliferation and metastasis by activating FAK/AKT signaling pathway
J Xu, W Zhang - Cancer cell international, 2021 - Springer
Background As a member of the ERM (ezrin-radixin-moesin) protein family, EZR has been
recognized as a regulator of adhesion signal pathways by researchers. Moreover, EZR was …
recognized as a regulator of adhesion signal pathways by researchers. Moreover, EZR was …
[HTML][HTML] Perspectives for Targeting Ezrin in Cancer Development and Progression
JC Lipreri da Silva, HP Vicari, JA Machado-Neto - Future Pharmacology, 2023 - mdpi.com
Recent advances have been made in understanding molecular markers involved in cancer
malignancy, resulting in better tumor staging and identifying new potential therapeutic …
malignancy, resulting in better tumor staging and identifying new potential therapeutic …
[HTML][HTML] TMED3 promotes the progression and development of lung squamous cell carcinoma by regulating EZR
A Xie, X Xu, P Kuang, L Zhang, F Yu - Cell Death & Disease, 2021 - nature.com
Lung squamous cell carcinoma (LUSC) has a poor clinical prognosis and lacks effective
targeted therapy. The transmembrane emp24 trafficking protein 3 (TMED3) belongs to the …
targeted therapy. The transmembrane emp24 trafficking protein 3 (TMED3) belongs to the …
[HTML][HTML] A novel tumor-associated neutrophil gene signature for predicting prognosis, tumor immune microenvironment, and therapeutic response in breast cancer
J Zhang, X Wang, Z Zhang, F Ma, F Wang - Scientific Reports, 2024 - nature.com
Tumor-associated neutrophils (TANs) can promote tumor progression. This study aimed to
investigate the molecular signature that predict the prognosis and immune response of …
investigate the molecular signature that predict the prognosis and immune response of …
In vitro anti-motile effects of Rhoifolin, a flavonoid extracted from Callicarpa nudiflora on breast cancer cells via downregulating Podocalyxin-Ezrin interaction during …
L Xiong, H Lu, Y Hu, W Wang, R Liu, X Wan, J Fu - Phytomedicine, 2021 - Elsevier
Background Callicarpa nudiflora (C. nudiflora), which is a medical herb in genus of
Callicarpa, widely grows in the southern part of China. Several investigations had shown …
Callicarpa, widely grows in the southern part of China. Several investigations had shown …
[Retracted] Integrated Analysis of Circular RNA‐Associated ceRNA Network Reveals Potential circRNA Biomarkers in Human Breast Cancer
H Sheng, H Pan, M Yao, L Xu, J Lu… - … Methods in Medicine, 2021 - Wiley Online Library
Circular RNA (circRNA) is closely related to tumorigenesis and cancer progression. Yet, the
roles of cancer‐specific circRNAs in the circRNA‐related ceRNA network of breast cancer …
roles of cancer‐specific circRNAs in the circRNA‐related ceRNA network of breast cancer …
Ezrin accelerates breast cancer liver metastasis through promoting furin-like convertase-mediated cleavage of Notch1
M Chen, Y Pan, H Liu, F Ning, Q Lu, Y Duan, X Gan… - Cellular Oncology, 2023 - Springer
Background Ezrin, known as a crosslinker between the plasma membrane and actin
cytoskeleton, is closely associated with breast cancer (BC) progression. Here, we explored a …
cytoskeleton, is closely associated with breast cancer (BC) progression. Here, we explored a …
[HTML][HTML] circCDYL2, overexpressed in highly migratory colorectal Cancer cells, promotes migration by binding to Ezrin
X Li, J Wang, H Long, W Lin, H Wang, Y Chen… - Frontiers in …, 2021 - frontiersin.org
Background Colorectal cancer (CRC) is one of the most common malignancies with high
mortality worldwide, particularly due to metastasis. However, there are no clinically available …
mortality worldwide, particularly due to metastasis. However, there are no clinically available …
[HTML][HTML] Comparative gene signature of (−)-oleocanthal formulation treatments in heterogeneous triple negative breast tumor models: Oncological therapeutic target …
Triple negative breast cancer (TNBC) heterogeneity and limited therapeutic options confer
its phenotypic aggressiveness. The discovery of anti-TNBC natural products with valid …
its phenotypic aggressiveness. The discovery of anti-TNBC natural products with valid …
Breast Cancer Therapeutics and Hippo Signaling Pathway: Novel MicroRNA-Gene-Protein Interaction Networks
The Hippo signaling pathway is a master regulator of development, cell proliferation, and
apoptosis in particular, and it plays an important role in tissue regeneration, controlling …
apoptosis in particular, and it plays an important role in tissue regeneration, controlling …