Animal models are necessary to identify pathological changes and help assess therapeutic
outcomes following spinal cord injury (SCI). Small animal models offer value in research in …

Spinal cord injury (SCI) is a devastating disease with limited effective treatment options.
Animal paradigms are vital for understanding the pathogenesis of SCI and testing potential …

Background: Pathological changes associated with spinal cord injury (SCI) can be observed
distant, rostral, or caudal to the epicenter of injury. These remote areas represent important …

CRISPR/Cas9 system has been used as the most powerful gene editing tool for precision
medicine and advanced gene therapy. However, its wide applications are limited by the …

The contemporary strategy for spinal cord injury (SCI) therapy aims to combine multiple
approaches to control pathogenic mechanisms of neurodegeneration and stimulate …

Currently, the main fundamental and clinical interest for stroke therapy is focused on
developing a neuroprotective treatment of a penumbra region within the therapeutic window …

The natural limitations of regeneration in the CNS are major problems for the treatment of
neurological disorders, including ischaemic brain strokes. Among the approaches being …

Resistance to antibacterial therapy requires the discovery of new methods for the treatment
of infectious diseases. Lactoferrin (LTF) is a well-known naïve first-line defense protein. In …

Post-traumatic spinal cord remodeling includes both degenerating and regenerating
processes, which affect the potency of the functional recovery after spinal cord injury (SCI) …

Epidural electrical stimulation is a new treatment method for spinal cord injury (SCI). Its
efficacy and safety have previously been reported. Rehabilitation treatment after epidural …