During the early phase of the coronavirus disease 2019 (COVID-19) pandemic, design,
development, validation, verification and implementation of diagnostic tests were actively …

Meta-transcriptomic next-generation sequencing has transformed virus discovery,
dramatically expanding our knowledge of the known virosphere. Nevertheless, the use of …

The increasing prevalence and expanding distribution of tick-borne viruses globally have
raised health concerns, but the full repertoire of the tick virome has not been assessed. We …

Although millions of distinct virus species likely exist, only approximately 9000 are
catalogued in GenBank's RefSeq database. We selectively enriched for the genomes of …

Numerous studies have identified microbial sequences or epitopes in pathological and non-
pathological human brain samples. It has not been resolved if these observations are …

Virus discovery has been fueled by new technologies ever since the first viruses were
discovered at the end of the 19th century. Starting with mechanical devices that provided …

Metagenomic high-throughput sequencing (mHTS) is a hypothesis-free, universal pathogen
detection technique for determination of the DNA/RNA sequences in a variety of sample …

High‐throughput sequencing (HTS) is a powerful tool that enables the simultaneous
detection and potential identification of any organisms present in a sample. The growing …

Despite its isolation and extreme climate, Antarctica is home to diverse fauna and
associated microorganisms. It has been proposed that the most iconic Antarctic animal, the …

Human blood metagenomics has revealed the presence of different types of viruses in
apparently healthy subjects. By far, anelloviruses constitute the viral family that is more …