Molecular characterisation of the mechanism of action of stimulant drugs lisdexamfetamine and methylphenidate on ADHD neurobiology: A review

J Quintero, JR Gutiérrez-Casares, C Álamo - Neurology and therapy, 2022 - Springer
Attention-deficit/hyperactivity disorder (ADHD) is a common childhood-onset
neurodevelopmental disorder characterised by persistent inattention, hyperactivity and …

Norepinephrine system at the interface of attention and reward

Y Zhang, Y Chen, Y Xin, B Peng, S Liu - Progress in Neuro …, 2023 - Elsevier
Reward learning is key to survival for individuals. Attention plays an important role in the
rapid recognition of reward cues and establishment of reward memories. Reward history …

[HTML][HTML] Genetics in the ADHD clinic: how can genetic testing support the current clinical practice?

L Balogh, AJ Pulay, JM Réthelyi - Frontiers in Psychology, 2022 - frontiersin.org
Attention-deficit/hyperactivity disorder (ADHD) is a neurodevelopmental disorder with a
childhood prevalence of 5%. In about two-thirds of the cases, ADHD symptoms persist into …

Genetic influence on efficacy of pharmacotherapy for pediatric attention-deficit/hyperactivity disorder: overview and current status of research

NA Elsayed, KM Yamamoto, TE Froehlich - CNS drugs, 2020 - Springer
Multiple stimulant and non-stimulant medications are approved for the treatment of attention-
deficit/hyperactivity disorder (ADHD), one of the most prevalent childhood …

PharmGKB summary: methylphenidate pathway, pharmacokinetics/pharmacodynamics

T Stevens, K Sangkuhl, JT Brown… - Pharmacogenetics …, 2019 - journals.lww.com
Overview Methylphenidate (MPH) is a central nervous system stimulant primarily used for
the treatment of attention deficit hyperactivity disorder (ADHD). MPH works by preventing the …

Noradrenergic genes polymorphisms and response to methylphenidate in children with ADHD: a systematic review and meta-analysis

D Yuan, M Zhang, Y Huang, X Wang, J Jiao, Y Huang - Medicine, 2021 - journals.lww.com
Background: Attention-deficit hyperactivity disorder (ADHD) is the most common childhood-
onset neurodevelopmental disorder, and methylphenidate (MPH) is considered one of the …

Deep sequencing of candidate genes identified 14 variants associated with smoking abstinence in an ethnically diverse sample

PM Cinciripini, DW Wetter, J Wang, R Yu… - Scientific reports, 2024 - nature.com
Despite the large public health toll of smoking, genetic studies of smoking cessation have
been limited with few discoveries of risk or protective loci. We investigated common and rare …

Assessment of associations between mitochondrial DNA haplogroups and attention deficit and hyperactivity disorder in Korean children

IW Hwang, BN Kwon, HJ Kim, SH Han, NR Lee… - Mitochondrion, 2019 - Elsevier
Attention deficit hyperactivity disorder (ADHD) is a multifactorial disorder with multiple
environmental and biological etiologies, including genetic factors. Until now, several genetic …

CES1 and SLC6A2 genetic variants as predictors of response to methylphenidate in autism spectrum disorders

MH Hernandez, V Bote, A Serra-LLovich… - Pharmacogenomics …, 2022 - Taylor & Francis
Purpose Autistic spectrum disorders (ASD) children and adolescents usually present
comorbidities, with 40–70% of them affected by attention deficit hyperactivity disorders …

VMAT2 gene (SLC18A2) variants associated with a greater risk for developing opioid dependence

M Randesi, W van den Brink, O Levran… - …, 2019 - Future Medicine
Aim: To determine if selected serotonergic and noradrenergic gene variants are associated
with heroin addiction. Subjects & methods: A total of 126 variants in 19 genes in subjects …