The Role of ncRNAs in the Immune Dysregulation of Preeclampsia

C Mora-Palazuelos, CE Villegas-Mercado… - International Journal of …, 2023 - mdpi.com
The main complications causing practically 75% of all maternal deaths are severe bleeding,
infections, and high blood pressure during pregnancy (preeclampsia (PE) and eclampsia) …

Advances in pathogenesis of preeclampsia

M Yang, M Wang, N Li - Archives of Gynecology and Obstetrics, 2024 - Springer
Purpose Preeclampsia is a major cause of health problems for both pregnant women and
unborn babies worldwide. However, the underlying causes of preeclampsia are not fully …

Regulatory roles of non-coding RNAs and m6A modification in trophoblast functions and the occurrence of its related adverse pregnancy outcomes

W Rong, W Shukun, W Xiaoqing, H Wenxin… - Critical Reviews in …, 2022 - Taylor & Francis
Adverse pregnancy outcomes, such as preeclampsia, gestational diabetes mellitus, fetal
growth restriction, and recurrent miscarriage, occur frequently in pregnant women and might …

The role of long non-coding rnas in trophoblast regulation in preeclampsia and intrauterine growth restriction

LJ Monteiro, R Peñailillo, M Sánchez… - Genes, 2021 - mdpi.com
Preeclampsia (PE) and Intrauterine Growth Restriction (IUGR) are two pregnancy-specific
placental disorders with high maternal, fetal, and neonatal morbidity and mortality rates …

The long noncoding RNA TARID regulates the CXCL3/ERK/MAPK pathway in trophoblasts and is associated with preeclampsia

L Liao, M Liu, Y Gao, X Wei, Y Yin, L Gao… - Reproductive Biology and …, 2022 - Springer
Background The widely accepted explanation of preeclampsia (PE) pathogenesis is
insufficient trophoblast invasion and impaired uterine spiral artery remodeling. However, the …

Long non-coding RNAs: a summary of their roles in placenta development and pathology

EA Adu-Gyamfi, EA Cheeran, J Salamah… - Biology of …, 2024 - academic.oup.com
Long non-coding RNAs are cellular transcripts that have˃ 200 nucleotides in length and do
not code for proteins. Due to their low expression levels, long non-coding RNAs were …

Biogenesis and function of exosome lncRNAs and their role in female pathological pregnancy

M Wang, L Zheng, S Ma, R Lin, J Li… - Frontiers in …, 2023 - frontiersin.org
Preeclampsia, gestational diabetes mellitus, and recurrent spontaneous abortion are
common maternal pregnancy complications that seriously endanger women's lives and …

lncRNA PROX1-AS1 mediates the migration and invasion of placental trophoblast cells via the miR-211-5p/caspase-9 axis

D Tang, L Geng, J Ma - Bioengineered, 2021 - Taylor & Francis
Preeclampsia (PE) is a potentially fatal pregnancy complication; however, its pathogenesis
remains unclear. Long non-coding RNAs (lncRNAs) are associated with occurrence and …

Bioinformatics analysis combined with clinical sample screening reveals that leptin may be a biomarker of preeclampsia

Y Wang, X Bai, X Guo, X Gao, Y Chen, H Li… - Frontiers in …, 2023 - frontiersin.org
Introduction: Preeclampsia (PE) is a gestational hypertensive disease with unclear
pathogenesis. This study aimed to identify the genes that play an important role in …

MALAT1 modulates trophoblast phenotype via miR-101–3p/VEGFA axis

Q Li, S Li, J Ding, B Pang, R Li, H Cao, L Ling - Archives of Biochemistry …, 2023 - Elsevier
Preeclampsia is a potentially life-threatening condition that can arise due to poor
placentation and consequent abnormal uterine spiral artery remodeling. Abnormal …