[HTML][HTML] The consensus from The Chinese Society of Hematology on indications, conditioning regimens and donor selection for allogeneic hematopoietic stem cell …

X Zhang, J Chen, MZ Han, H Huang, E Jiang… - Journal of hematology & …, 2021 - Springer
The consensus recommendations in 2018 from The Chinese Society of Hematology (CSH)
on indications, conditioning regimens and donor selection for allogeneic hematopoietic stem …

Haematopoietic stem-cell transplantation in China in the era of targeted therapies: current advances, challenges, and future directions

YJ Chang, XY Pei, XJ Huang - The Lancet Haematology, 2022 - thelancet.com
In the era of targeted therapies, haematopoietic stem-cell transplantation (HSCT), both
allogeneic and autologous, remains a curative approach for patients with chemosensitive …

Sorafenib maintenance in patients with FLT3-ITD acute myeloid leukaemia undergoing allogeneic haematopoietic stem-cell transplantation: an open-label …

L Xuan, Y Wang, F Huang, Z Fan, Y Xu, J Sun… - The Lancet …, 2020 - thelancet.com
Background Findings of retrospective studies suggest that sorafenib maintenance post-
transplantation might reduce relapse in patients with FLT3 internal tandem duplication (FLT3 …

[HTML][HTML] Venetoclax combined with azacitidine and homoharringtonine in relapsed/refractory AML: a multicenter, phase 2 trial

H Jin, Y Zhang, S Yu, X Du, N Xu, R Shao, D Lin… - Journal of Hematology & …, 2023 - Springer
Background Relapsed or refractory acute myeloid leukemia (R/R AML) has a dismal
prognosis. The aim of this study was to investigate the activity and tolerability of venetoclax …

Dynamic immune profiling identifies the stronger graft-versus-leukemia (GVL) effects with haploidentical allografts compared to HLA-matched stem cell transplantation

H Guo, YJ Chang, Y Hong, LP Xu, Y Wang… - Cellular & molecular …, 2021 - nature.com
Haploidentical stem cell transplantation (haplo-SCT) achieves superior or at least
comparable clinical outcomes to HLA-matched sibling donor transplantation (MSDT) in …

[HTML][HTML] MRD tailored therapy in AML: what we have learned so far

LL Ngai, A Kelder, JJWM Janssen… - Frontiers in …, 2021 - frontiersin.org
Acute myeloid leukemia (AML) is a heterogeneous clonal disease associated with a dismal
survival, partly due to the frequent occurrence of relapse. Many patient-and leukemia …

[HTML][HTML] Post-transplant cyclophosphamide after matched sibling, unrelated and haploidentical donor transplants in patients with acute myeloid leukemia: a …

J Sanz, JE Galimard, M Labopin, B Afanasyev… - Journal of hematology & …, 2020 - Springer
Background The use of post-transplant cyclophosphamide (PTCy) is highly effective in
preventing graft-versus-host disease (GVHD) in the haploidentical (Haplo) transplant setting …

Genetic characteristics predict response to venetoclax plus hypomethylating agents in relapsed or refractory acute myeloid leukemia

G Weng, Y Zhang, G Yu, T Luo, S Yu… - Journal of Internal …, 2023 - Wiley Online Library
Background The heterogeneity of relapsed or refractory (R/R) acute myeloid leukemia (AML)
leads to no response to venetoclax (VEN)–based therapy in more than half of the patients …

A personalized approach to guide allogeneic stem cell transplantation in younger adults with acute myeloid leukemia

L Fenwarth, X Thomas, S De Botton… - Blood, The Journal …, 2021 - ashpublications.org
A multistage model instructed by a large dataset (knowledge bank [KB] algorithm) has
recently been developed to improve outcome predictions and tailor therapeutic decisions …

[HTML][HTML] Haploidentical versus HLA-matched sibling transplantation for refractory acute leukemia undergoing sequential intensified conditioning followed by DLI: an …

S Yu, F Huang, Z Fan, L Xuan, D Nie, Y Xu… - Journal of Hematology & …, 2020 - Springer
Background Compared with HLA-matched sibling donor (MSD) transplant, the outcomes of
haploidentical donor (HID) transplant for refractory acute leukemia need to be further …