There is an unmet need for novel and efficacious therapeutics for regenerating injured
articular cartilage in progressive osteoarthritis (OA) and/or trauma. Mesenchymal stem cells …

Osteoarthritis (OA) is a joint condition that causes significant impairment of the chondrocyte.
The gradual degradation of the cartilage lining of one or more freely moving joints, as well …

Background: Studies with extracellular vesicles (EVs), including exosomes, isolated from
mesenchymal stem cells (MSC) indicate benefits for the treatment of musculoskeletal …

Abstract Background: Mesenchymal stem cells (MSCs) are used for tissue regeneration due
to their wide differentiation capacity and anti-inflammatory effects. Extracellular vesicles …

Anthocyanins are known to change ligand-receptor bindings, cell membrane permeability,
and intracellular signaling pathways. The beneficial effects of dietary anthocyanins have …

Mesenchymal stem cells (MSCs) are considered a promising candidate for use in cell‐
based therapy for cartilage repair. To promote understanding of the molecular control of …

Background The potential for cartilage repair using articular cartilage derived
chondroprogenitors has recently gained popularity due to promising results from in-vitro and …

Osteoarthritis (OA) is the most common degenerative joint disease that causes chronic pain
and disability. Different innate immune components, including macrophages, T cells, and …

Cellular therapy offers regeneration which curbs osteoarthritis of the knee. Among cellular
therapies, mesenchymal stromal cells (MSCs) are readily isolated from various sources as …

Osteoarthritis (OA) is a globally occurring articular cartilage degeneration disease that
adversely affects both the physical and mental well-being of the patient, including limited …