Surfactants are essential in the manufacture of polymeric nanoparticles by emulsion
formation methods and to preserve the stability of carriers in liquid media. The deposition of …

Abstract Design of experiment (DoE) is a powerful statistical technique used for variable
screening and optimization. It is based on the simultaneous variation of multiple factors with …

The absorption of orally administered drug products is a complex, dynamic process,
dependant on a range of biopharmaceutical properties; notably the aqueous solubility of a …

The solid self-nanoemulsifying drug delivery system (s-SNEDDS) is a growing platform for
the delivery of drugs via oral route. In the present work, tamoxifen (TAM) was loaded in …

Since the emergence of Soluplus®(SOL) as a commercial graft copolymer, multiple
publications have been issued on its promising potential as a solubilizing excipient that …

Purpose Etodolac (ETD) is one of the non-steroidal anti-inflammatory drugs which has low
aqueous solubility issues. The objective of this study was to develop ETD nanosuspensions …

The goal of this work was to improve the aqueous solubility and dissolution rate of
eprosartan mesylate by preparing inclusion complex of drug with β-cyclodextrin (β-CD) by …

Abstract Background Quality by Design (QbD) is a pharmaceutical quality management
system that predicts, controls, and systematically responds to risks that may occur in the …

Niosomes are multilamellar vesicles that effectively transfer active ingredients into the skin's
layers. To improve the active substance's penetration across the skin, these carriers are …

Cilnidipine (CLD) is extensively used in the treatment of hypertension; however, it has
extremely low solubility which limits its clinical application. The purpose of the present …