Cannabinoids as novel anti-inflammatory drugs

P Nagarkatti, R Pandey, SA Rieder… - Future medicinal …, 2009 - Taylor & Francis
Cannabinoids are a group of compounds that mediate their effects through cannabinoid
receptors. The discovery of Δ9-tetrahydrocannabinol (THC) as the major psychoactive …

Transverse myelitis

SC Beh, BM Greenberg, T Frohman… - Neurologic …, 2013 - neurologic.theclinics.com
Acute noncompressive myelopathies have been recognized since the nineteenth century. 1
The terms myelitis and myelopathy are often used interchangeably, but have different …

Cannabinoid-induced apoptosis in immune cells as a pathway to immunosuppression

SA Rieder, A Chauhan, U Singh, M Nagarkatti… - Immunobiology, 2010 - Elsevier
Cannabinoids are a group of compounds present in Cannabis plant (Cannabis sativa L.).
They mediate their physiological and behavioral effects by activating specific cannabinoid …

[HTML][HTML] Trigeminal neuralgia secondary to multiple sclerosis: from the clinical picture to the treatment options

G Di Stefano, S Maarbjerg, A Truini - The journal of headache and pain, 2019 - Springer
Background Trigeminal neuralgia is one of the most characteristic and difficult to treat
neuropathic pain conditions in patients with multiple sclerosis. The present narrative review …

[HTML][HTML] The analgesic potential of cannabinoids

J Elikottil, P Gupta, K Gupta - Journal of opioid management, 2009 - ncbi.nlm.nih.gov
Historically and anecdotally cannabinoids have been used as analgesic agents. In recent
years, there has been an escalating interest in developing cannabis-derived medications to …

Therapeutic prospects of cannabinoids in the immunomodulation of prevalent autoimmune diseases

XM Rodriguez Mesa, AF Moreno Vergara… - Cannabis and …, 2021 - liebertpub.com
Introduction: Cannabinoids such as▵-9-THC and CBD can downregulate the immune
response by modulating the endocannabinoid system. This modulation is relevant for the …

[HTML][HTML] Characterizing chronic pain phenotypes in multiple sclerosis: a nationwide survey study

AL Kratz, D Whibley, KN Alschuler, DM Ehde… - Pain, 2021 - journals.lww.com
Chronic pain is highly prevalent in multiple sclerosis (MS). Pain heterogeneity may
contribute to poor treatment outcomes. The aim of this study was to characterize pain …

Evaluating Sativex® in Neuropathic Pain Management: A Clinical and Neurophysiological Assessment in Multiple Sclerosis

M Russo, A Naro, A Leo, E Sessa, G D'Aleo… - Pain …, 2016 - academic.oup.com
Objective. The aim of our study was to better investigate the role of Sativex® in improving
pain in multiple sclerosis (MS) patients by means of either clinical or neurophysiological …

Breaking peripheral immune tolerance to CNS antigens in neurodegenerative diseases: boosting autoimmunity to fight-off chronic neuroinflammation

M Schwartz, K Baruch - Journal of autoimmunity, 2014 - Elsevier
Immune cell infiltration to the brain's territory was considered for decades to reflect a
pathological process in which immune cells attack the central nervous system (CNS); such a …

Therapeutics for multiple sclerosis symptoms

AB Ben‐Zacharia - Mount Sinai Journal of Medicine: A Journal …, 2011 - Wiley Online Library
Symptoms management in multiple sclerosis is an integral part of its care. Accurate
assessment and addressing the different symptoms provides increased quality of life among …