How does a lack of sleep affect our brains? In contrast to the benefits of sleep, frameworks
exploring the impact of sleep loss are relatively lacking. Importantly, the effects of sleep …

The classification of sleep disorders is necessary to discriminate between disorders and to
facilitate an understanding of symptoms, etiology, and pathophysiology that allows for …

Importance Sleep disturbances are most prevalent among older adults and often go
untreated. Treatment options for sleep disturbances remain limited, and there is a need for …

Several theories claim that dreaming is a random by-product of REM sleep physiology and
that it does not serve any natural function. Phenomenal dream content, however, is not as …

The overall function of sleep is hypothesized to provide “recovery” after preceding waking
activities, thereby ensuring optimal functioning during subsequent wakefulness. However …

There is growing interest in insomnia both from the perspective of recent advances in clinical
management as well as research aimed at elucidating its pathophysiology. This theoretical …

Background The aim was to examine the prevalence and consequences of co-occurring
insomnia and hypersomnia symptoms in depressed adults drawn from a representative …

Introduction: Chronic medicated patients with schizophrenia have marked reductions in
sleep spindle activity and a correlated deficit in sleep-dependent memory consolidation …

Chronic stress is linked to development of depression and may trigger neurobiological
changes underlying the disease. Downregulation of the secretory peptide brain-derived …

The neuropeptides orexins are important in regulating the neurobiological systems that
respond to stressful stimuli. Furthermore, orexins are known to play a role many of the …