The methods for the culture and cardiomyocyte differentiation of human embryonic stem
cells, and later human induced pluripotent stem cells (hiPSC), have moved from a complex …

The human heart has the least regenerative capabilities among tissues and organs, and
heart disease continues to be a leading cause of mortality in the industrialized world with …

Human pluripotent stem cell (hPSC) technology has offered nearly infinite opportunities to
model all kinds of human diseases in vitro. Cardiomyocytes derived from hPSCs have …

During cardiac development and morphogenesis, cardiac progenitor cells differentiate into
cardiomyocytes that expand in number and size to generate the fully formed heart. Much is …

In vitro modelling the complex (patho‐) physiological conditions of the heart is a major
challenge in cardiovascular research. In recent years, methods based on three‐dimensional …

Heart regeneration addresses a central problem in cardiology, the irreversibility of the loss of
myocardium that eventually leads to heart failure. True restoration of heart function can only …

Human pluripotent stem cell-derived cardiovascular progenitor cells (hCVPCs) and
cardiomyocytes (hCMs) possess therapeutic potential for infarcted hearts; however, their …

Background: Transplantation of pluripotent stem cell–derived cardiomyocytes represents a
promising therapeutic strategy for cardiac regeneration, and the first clinical studies in …

Cardiovascular disease is a leading cause of disability and death worldwide. Although the
survival rate of patients with heart diseases can be improved with contemporary …

Abstract 3D‐bioprinting is a promising technology to produce human tissues as drug
screening tool or for organ repair. However, direct printing of living cells has proven difficult …