Novel insights into the molecular mechanisms of atherosclerosis

A Wojtasińska, W Frąk, W Lisińska, N Sapeda… - International Journal of …, 2023 - mdpi.com
Atherosclerosis is one of the most fatal diseases in the world. The associated thickening of
the arterial wall and its background and consequences make it a very composite disease …

Hydrogen Sulfide and Oxygen Homeostasis in Atherosclerosis: A Systematic Review from Molecular Biology to Therapeutic Perspectives

C Munteanu - International Journal of Molecular Sciences, 2023 - mdpi.com
Atherosclerosis is a complex pathological condition marked by the accumulation of lipids in
the arterial wall, leading to the development of plaques that can eventually rupture and …

[HTML][HTML] Mitochondria as intracellular signalling organelles. An update

LD Popov - Cellular Signalling, 2023 - Elsevier
Traditionally, mitochondria are known as" the powerhouse of the cell," responsible for
energy (ATP) generation (by the electron transport chain, oxidative phosphorylation, the …

The multi-faceted nature of renalase for mitochondrial dysfunction improvement in cardiac disease

D Stojanovic, M Stojanovic, J Milenkovic, A Velickov… - Cells, 2023 - mdpi.com
The cellular mechanisms and signaling network that guide the cardiac disease
pathophysiology are inextricably intertwined, which explains the current scarcity of effective …

Targeting mitochondrial function in macrophages: A novel treatment strategy for atherosclerotic cardiovascular disease?

PH Becker, P Thérond, P Gaignard - Pharmacology & Therapeutics, 2023 - Elsevier
Atherosclerotic cardiovascular disease is a major cause of morbidity and mortality due to
chronic arterial injury caused by hyperlipidemia, hypertension, inflammation and oxidative …

Glucose-Lowering Effects of Imeglimin and Its Possible Beneficial Effects on Diabetic Complications

H Yanai, H Adachi, M Hakoshima, H Katsuyama - Biology, 2023 - mdpi.com
Simple Summary Mitochondria are organelles found in the cells of animals. Mitochondria
use aerobic respiration to generate adenosine triphosphate. Mitochondrial dysfunction is a …

Copper homeostasis and cuproptosis in atherosclerosis: metabolism, mechanisms and potential therapeutic strategies

S Yang, Y Li, L Zhou, X Wang, L Liu, M Wu - Cell Death Discovery, 2024 - nature.com
Copper is an essential micronutrient that plays a pivotal role in numerous physiological
processes in virtually all cell types. Nevertheless, the dysregulation of copper homeostasis …

RhoA/ROCK1 regulates the mitochondrial dysfunction through Drp1 induced by Porphyromonas gingivalis in endothelial cells

Q Dong, Y Luo, Y Yin, Y Ma, Y Yu… - Journal of Cellular …, 2023 - Wiley Online Library
Porphyromonas gingivalis (P. gingivalis) is a pivotal pathogen of periodontitis. Our previous
studies have confirmed that mitochondrial dysfunction in the endothelial cells caused by P …

Blood Monocyte Phenotype Is A Marker of Cardiovascular Risk in Type 2 Diabetes

JB Julla, D Girard, M Diedisheim, PJ Saulnier… - Circulation …, 2024 - Am Heart Assoc
BACKGROUND: Diabetes is a major risk factor for atherosclerotic cardiovascular diseases
with a 2-fold higher risk of cardiovascular events in people with diabetes compared with …

Role of polyphenolic compounds and their nanoformulations: A comprehensive review on cross-talk between chronic kidney and cardiovascular diseases

A Rajput, P Sharma, D Singh, S Singh, P Kaur… - Naunyn-Schmiedeberg's …, 2023 - Springer
Chronic kidney disease (CKD) affects a huge portion of the world's population and
frequently leads to cardiovascular diseases (CVDs). It might be because of common risk …