The therapeutic properties of plants have been recognised since time immemorial. Many
pathological conditions have been treated using plant-derived medicines. These medicines …

Recent advances in mass spectrometry (MS)-based proteomics have enabled tremendous
progress in the understanding of cellular mechanisms, disease progression, and the …

Exosomes are extracellular vesicles derived from the endosomal compartment that are
potentially involved in intercellular communication. Here, we found that frequently used …

Metabolic rewiring is often considered an adaptive pressure limiting metastasis formation;
however, some nutrients available at distant organs may inherently promote metastatic …

Many long non-coding RNAs (lncRNAs) affect gene expression, but the mechanisms by
which they act are still largely unknown. One of the best-studied lncRNAs is Xist, which is …

Industrialization, population burst, and changing lifestyles have resulted in the genesis of
non-degradable pollutants languishing the environment and human health. Biological …

Covering: 2010 up to 2016 Deconvoluting the mode of action of natural products and drugs
remains one of the biggest challenges in chemistry and biology today. Chemical proteomics …

Mass-spectrometry-based proteomics is continuing to make major contributions to the
discovery of fundamental biological processes and, more recently, has also developed into …

ADP-ribosylation (ADPr) is a posttranslational modification (PTM) of proteins that controls
many cellular processes, including DNA repair, transcription, chromatin regulation and …

SILAC is based on direct addition of selected stable isotope amino acids into the cell culture
medium, allowing superior quantitative analysis of the cellular proteome compared to other …