Efficient production of reactive oxygen species in neural precursor cells after exposure to 250 MeV protons
E Giedzinski, R Rola, JR Fike… - Radiation …, 2005 - meridian.allenpress.com
Abstract Giedzinski, E., Rola, R., Fike, JR and Limoli, CL Efficient Production of Reactive
Oxygen Species in Neural Precursor Cells after Exposure to 250 MeV Protons. Radiat. Res …
Oxygen Species in Neural Precursor Cells after Exposure to 250 MeV Protons. Radiat. Res …
An anti‐CD11d integrin antibody reduces cyclooxygenase‐2 expression and protein and DNA oxidation after spinal cord injury in rats
F Bao, Y Chen, GA Dekaban… - Journal of …, 2004 - Wiley Online Library
Our studies have shown that treatment with a monoclonal antibody (mAb) against the
CD11d subunit of the leukocyte integrin CD11d/CD18 after spinal cord injury (SCI) …
CD11d subunit of the leukocyte integrin CD11d/CD18 after spinal cord injury (SCI) …
Proteomic study of amyloid beta (25–35) peptide exposure to neuronal cells: Impact on APE1/Ref‐1's protein–protein interaction
The genotoxic, extracellular accumulation of amyloid β (Aβ) protein and subsequent
neuronal cell death are associated with Alzheimer's disease (AD). APE1/Ref‐1, the …
neuronal cell death are associated with Alzheimer's disease (AD). APE1/Ref‐1, the …
Prevention of mitochondrial dysfunction in post‐traumatic mouse brain by superoxide dismutase
Y Xiong, FS Shie, J Zhang, CP Lee… - Journal of …, 2005 - Wiley Online Library
Reactive oxygen species (ROS) are known to be involved in the pathogenesis of traumatic
brain injury (TBI). Previous studies have shown that the susceptibility of mice to TBI‐induced …
brain injury (TBI). Previous studies have shown that the susceptibility of mice to TBI‐induced …
C1q–calreticulin induced oxidative neurotoxicity: relevance for the neuropathogenesis of Alzheimer's disease
X Luo, GA Weber, J Zheng, HE Gendelman… - Journal of …, 2003 - Elsevier
Alzheimer's disease (AD) remains one of the most challenging brain disorders facing
modern medicine. Neuronal loss underlies the pathogenesis of AD and can occur, in part, by …
modern medicine. Neuronal loss underlies the pathogenesis of AD and can occur, in part, by …
The protective role of cellular glutathione peroxidase against trauma-induced mitochondrial dysfunction in the mouse brain
Y Xiong, FS Shie, J Zhang, CP Lee, YS Ho - Journal of Stroke and …, 2004 - Elsevier
Reactive oxygen species are believed to participate in the pathogenesis of traumatic brain
injury (TBI). To evaluate the role of cellular glutathione peroxidase (Gpx1), a selenium …
injury (TBI). To evaluate the role of cellular glutathione peroxidase (Gpx1), a selenium …
A therapeutic time window for anti-CD11d monoclonal antibody treatment yielding reduced secondary tissue damage and enhanced behavioral recovery following …
DS Ditor, F Bao, Y Chen, GA Dekaban… - Journal of Neurosurgery …, 2006 - thejns.org
Object The purpose of this study was to investigate the therapeutic time window for
antiinflammatory treatment within the first 24 hours of spinal cord injury (SCI). The authors …
antiinflammatory treatment within the first 24 hours of spinal cord injury (SCI). The authors …
The redox function of APE1 is involved in the differentiation process of stem cells toward a neuronal cell fate
R Domenis, N Bergamin, G Gianfranceschi… - PLoS …, 2014 - journals.plos.org
Low-to-moderate levels of reactive oxygen species (ROS) govern different steps of
neurogenesis via molecular pathways that have been decrypted only partially. Although it …
neurogenesis via molecular pathways that have been decrypted only partially. Although it …
Apurinic/apyrimidinic endonuclease 1 upregulation reduces oxidative DNA damage and protects hippocampal neurons from ischemic injury
Abstract Aims: Apurinic/apyrimidinic endonuclease 1 (APE1) is a multifunctional enzyme that
participates in base-excision repair of oxidative DNA damage and in the redox activation of …
participates in base-excision repair of oxidative DNA damage and in the redox activation of …
Ape1/Ref-1 induces glial cell-derived neurotropic factor (GDNF) responsiveness by upregulating GDNF receptor α1 expression
Abstract Apurinic/apyrimidinic endonuclease 1 (Ape1/Ref-1) dysregulation has been
identified in several human tumors and in patients with a variety of neurodegenerative …
identified in several human tumors and in patients with a variety of neurodegenerative …