Treatment with dihydroethidium reduces infarct size after transient focal cerebral ischemia in mice
F Yu, T Sugawara, PH Chan - Brain research, 2003 - Elsevier
A transient focal ischemia model with C57Bl/6 mice was used to investigate whether
dihydroethidium is neuroprotective. Different doses (25, 50, 100 mg/kg body weight) were …
dihydroethidium is neuroprotective. Different doses (25, 50, 100 mg/kg body weight) were …
Effects of a manganese (III) porphyrin catalytic antioxidant in a mouse closed head injury model
SB Leinenweber, H Sheng, JR Lynch, H Wang… - European journal of …, 2006 - Elsevier
Closed head injury induces cerebral oxidative stress. The efficacy of a Mn (III) porphyrin
catalytic antioxidant was assessed in a mouse closed head injury model. Mice were …
catalytic antioxidant was assessed in a mouse closed head injury model. Mice were …
ALTERED LEVEL OF APURINIC/APYRIMIDINIC ENDONUCLEASE/REDOX FACTOR‐1 (APE/Ref‐1) mRNA IN THE HIPPOCAMPUS OF OVARIECTOMIZED RATS …
A Yalcin, L Kanit, G Durmaz, S Sargin… - Clinical and …, 2005 - Wiley Online Library
Accumulated clinical evidence suggests that selective oestrogen receptor modulators
(SERM), such as raloxifene, may be neuroprotective. Oxidative stress is a likely molecular …
(SERM), such as raloxifene, may be neuroprotective. Oxidative stress is a likely molecular …
The role of DNA damage and repair in neurotoxicity caused by cancer therapies
DB Duarte, MR Vasko - DNA Repair in Cancer Therapy, 2012 - Elsevier
Publisher Summary This chapter discusses the role of DNA damage and repair in
Neurotoxicity caused by cancer therapies. These therapies include ionizing radiation, the …
Neurotoxicity caused by cancer therapies. These therapies include ionizing radiation, the …
[HTML][HTML] Ape1/Ref-1 Stimulates GDNF/GFRα1-mediated Downstream Signaling and Neuroblastoma Proliferation
MY Kang, KY Kim, Y Yoon, Y Kang… - The Korean Journal …, 2009 - synapse.koreamed.org
We previously reported that glial cell line-derived neurotropic factor (GDNF) receptor α1
(GFRα1) is a direct target of apurinic/apyrimidinic endonuclease 1 (Ape1/Ref-1). In the …
(GFRα1) is a direct target of apurinic/apyrimidinic endonuclease 1 (Ape1/Ref-1). In the …
The role of DNA damage and repair in toxicity to postmitotic cells caused by cancer therapies
MR Vasko, B Shariati, N Zanville - DNA Repair in Cancer Therapy, 2016 - Elsevier
With increased survival rates for cancer patients, toxicity secondary to anticancer therapies
has become a prevalent clinical concern. Of major importance are toxicities occurring in …
has become a prevalent clinical concern. Of major importance are toxicities occurring in …
The male sexual revolution: independence from testosterone
JH Park, EF Rissman - Annual Review of Sex Research, 2007 - Taylor & Francis
Much of our knowledge concerning the physiology of male sexual behavior has been based
on classic work on animal models in which gonadal steroids are intimately tied to the …
on classic work on animal models in which gonadal steroids are intimately tied to the …
Brain expression of apurinic/apyrimidinic endonuclease (APE/Ref-1) multifunctional DNA repair enzyme gene in the mouse with special reference to the …
H Kimura, X Dong, K Yagita, H Okamura - Neuroscience research, 2003 - Elsevier
Multifunctional mammalian apurinic/apyrimidinic endonuclease (APE, also known as redox
factor-1; Ref-1) repairs baseless sites of damaged DNA caused by oxidative stress and …
factor-1; Ref-1) repairs baseless sites of damaged DNA caused by oxidative stress and …