Caloric restriction mimetics in nutrition and clinical trials

SJ Hofer, S Davinelli, M Bergmann, G Scapagnini… - Frontiers in …, 2021 - frontiersin.org
The human diet and dietary patterns are closely linked to the health status. High-calorie
Western-style diets have increasingly come under scrutiny as their caloric load and …

[HTML][HTML] What is the influence of grape products on liver enzymes? A systematic review and meta‐analysis of randomized controlled trials

S Ghaffar, MA Naqvi, A Fayyaz, MK Abid… - … Therapies in Medicine, 2022 - Elsevier
Highlights•We examined the effects of grape products supplementation on liver enzymes in
adults.•Grape products did not have any significant effects on ALT and AST levels.•More …

American Association of Clinical Endocrinology clinical practice guideline: developing a diabetes mellitus comprehensive care plan—2022 update

L Blonde, GE Umpierrez, SS Reddy, JB McGill… - Endocrine Practice, 2022 - Elsevier
Objective The objective of this clinical practice guideline is to provide updated and new
evidence-based recommendations for the comprehensive care of persons with diabetes …

The role of resveratrol in liver disease: A comprehensive review from in vitro to clinical trials

C Izzo, M Annunziata, G Melara, R Sciorio, M Dallio… - Nutrients, 2021 - mdpi.com
Many studies have shown that resveratrol has a lot of therapeutic effects on liver disorders.
Its administration can significantly increase the survival rate after liver transplantation …

Effects of the treatment with flavonoids on metabolic syndrome components in humans: A systematic review focusing on mechanisms of action

HJCB Gouveia, MV Urquiza-Martínez… - International journal of …, 2022 - mdpi.com
Diets high in bioactive compounds, such as polyphenols, have been used to mitigate
metabolic syndrome (MetS). Polyphenols are a large group of naturally occurring bioactive …

Stilbenes in grape berries and wine and their potential role as anti-obesity agents: A review

N Benbouguerra, R Hornedo-Ortega, F Garcia… - Trends in Food Science …, 2021 - Elsevier
Background Stilbenes are a group of naturally occurring phenolic compounds. These
compounds are synthetized by plants in response of biotic or abiotic stress situations. The …

Natural bioactive compounds useful in clinical management of metabolic syndrome

A Noce, M Di Lauro, F Di Daniele… - Nutrients, 2021 - mdpi.com
Metabolic syndrome (MetS) is a clinical manifestation characterized by a plethora of
comorbidities, including hyperglycemia, abdominal obesity, arterial hypertension, and …

The effect of resveratrol on blood lipid profile: A dose-response meta-analysis of randomized controlled trials

X Cao, W Liao, H Xia, S Wang, G Sun - Nutrients, 2022 - mdpi.com
(1) Background: The effects of resveratrol on blood lipids are controversial. Whether there is
a dose-response of the lipid profile upon resveratrol supplementation is unknown.(2) …

Targeting oxidative stress with polyphenols to fight liver diseases

IF Machado, RG Miranda, DJ Dorta, AP Rolo… - Antioxidants, 2023 - mdpi.com
Reactive oxygen species (ROS) are important second messengers in many metabolic
processes and signaling pathways. Disruption of the balance between ROS generation and …

Effect of resveratrol supplementation on hepatic steatosis and cardiovascular indices in overweight subjects with type 2 diabetes: a double-blind, randomized …

A Ali Sangouni, S Abdollahi… - BMC cardiovascular …, 2022 - Springer
Background Patients with type 2 diabetes mellitus (T2DM) are prone to develop non-
alcoholic fatty liver disease (NAFLD) and cardiovascular diseases (CVD). We aimed to …