[HTML][HTML] The roles of the SOX2 protein in the development of esophagus and esophageal squamous cell carcinoma, and pharmacological target for therapy

J Zhang, Z Wang, H Zhao, Y Wei, Y Zhou… - Biomedicine & …, 2023 - Elsevier
SOX2 is a transcription factor belonging to the SOX gene family, whose activity has been
associated with the maintenance of the stemness and self-renewal of embryonic stem cells …

The human long non-coding RNA LINC00941 and its modes of action in health and disease

E Morgenstern, M Kretz - Biological Chemistry, 2023 - degruyter.com
Long non-coding RNAs have gained attention in recent years as they were shown to play
crucial roles in the regulation of cellular processes, but the understanding of the exact …

Linc00941 fuels ribogenesis and protein synthesis by supporting robust cMYC translation in Malignant Pleural Mesothelioma

M Gugnoni, E Lorenzini, F Torricelli, B Donati… - Cancer Letters, 2024 - Elsevier
Malignant pleural mesothelioma is a rare and lethal cancer caused by exposure to asbestos.
The highly inflammatory environment caused by fibers accumulation forces cells to undergo …

The possible molecular mechanism underlying the involvement of the variable shear factor QKI in the epithelial-mesenchymal transformation of oesophageal cancer

Y Cui, Y Wu, Y Zhu, W Liu, L Huang, Z Hong, M Zhang… - Plos one, 2023 - journals.plos.org
Objective Based on the GEO, TCGA and GTEx databases, we reveal the possible molecular
mechanism of the variable shear factor QKI in epithelial mesenchymal transformation (EMT) …

The tale of SOX2: Focusing on lncRNA regulation in cancer progression and therapy

P Huang, F Wen, YS Li, Q Li - Life Sciences, 2024 - Elsevier
Long non-coding RNAs (lncRNAs) have emerged as influential contributors to diverse
cellular processes, which regulate gene function and expression via multiple mechanistic …

lncRNA LINC00941 modulates MTA2/NuRD occupancy to suppress premature human epidermal differentiation

E Morgenstern, C Molthof, U Schwartz… - Life Science …, 2024 - life-science-alliance.org
Numerous long non-coding RNAs (lncRNAs) were shown to have a functional impact on
cellular processes such as human epidermal homeostasis. However, the mechanism of …

[HTML][HTML] LncRNA-MUF: A Novel Oncogenic Star with Potential as a Biological Marker and Therapeutic Target for Gastrointestinal Malignancies

Y Wang, J Wang, Y Zhang, H Luo, H Yuan - Journal of Cancer, 2024 - ncbi.nlm.nih.gov
Gastrointestinal (GI) cancers pose a significant global health challenge, characterized by a
high incidence and poor prognosis. The delayed detection and occurrence of metastasis …

Y-Box Binding Protein 1: Unraveling the Multifaceted Role in Cancer Development and Therapeutic Potential

NTM Dinh, TM Nguyen, MK Park, CH Lee - International Journal of …, 2024 - mdpi.com
Y-box binding protein 1 (YBX1), a member of the Cold Shock Domain protein family, is
overexpressed in various human cancers and is recognized as an oncogenic gene …

Non‑coding RNA: A promising diagnostic biomarker and therapeutic target for esophageal squamous cell carcinoma

L Zhang, Y Wang, J Gao, X Zhou… - Oncology …, 2024 - spandidos-publications.com
Esophageal cancer (EC) is a common form of malignant tumor in the digestive system that is
classified into two types: Esophageal squamous cell carcinomas (ESCC) and esophageal …

LINC00941: a novel player involved in the progression of human cancers

Q Yan, X Su, Y Chen, Z Wang, W Han, Q Xia, Y Mao… - Human Cell, 2024 - Springer
LINC00941, also known as lncRNA-MUF, is an intergenic non-coding RNA located on
chromosome 12p11. 21. It actively participates in a complex competing endogenous RNA …