Opening doors with ultrasound and microbubbles: Beating biological barriers to promote drug delivery

J Deprez, G Lajoinie, Y Engelen, SC De Smedt… - Advanced drug delivery …, 2021 - Elsevier
Apart from its clinical use in imaging, ultrasound has been thoroughly investigated as a tool
to enhance drug delivery in a wide variety of applications. Therapeutic ultrasound, as such …

Physics of bubble oscillations

W Lauterborn, T Kurz - Reports on progress in physics, 2010 - iopscience.iop.org
Bubbles in liquids, soft and squeezy objects made of gas and vapour, yet so strong as to
destroy any material and so mysterious as at times turning into tiny light bulbs, are the topic …

Ultrasound‐propelled nanocups for drug delivery

JJ Kwan, R Myers, CM Coviello, SM Graham, AR Shah… - small, 2015 - Wiley Online Library
Ultrasound‐induced bubble activity (cavitation) has been recently shown to actively
transport and improve the distribution of therapeutic agents in tumors. However, existing …

[HTML][HTML] Ultrasound contrast imaging: Fundamentals and emerging technology

H Yusefi, B Helfield - Frontiers in Physics, 2022 - frontiersin.org
The development of microbubble contrast agents has broadened the scope of medical
ultrasound imaging. Along with dedicated imaging techniques, these agents provide …

Multiphase flow in microfluidics: From droplets and bubbles to the encapsulated structures

A Sattari, P Hanafizadeh, M Hoorfar - Advances in Colloid and Interface …, 2020 - Elsevier
Microfluidic technologies have a unique ability to control more precisely and effectively on
two-phase flow systems in comparison with macro systems. Controlling the size of the …

Targeted disruption of the blood–brain barrier with focused ultrasound: association with cavitation activity

N McDannold, N Vykhodtseva… - Physics in Medicine & …, 2006 - iopscience.iop.org
Acoustic emission was monitored during focused ultrasound exposures in conjunction with
an ultrasound contrast agent (Optison®) in order to determine if cavitation activity is …

Characterization of ultrasound contrast microbubbles using in vitro experiments and viscous and viscoelastic interface models for encapsulation

K Sarkar, WT Shi, D Chatterjee… - The Journal of the …, 2005 - pubs.aip.org
Zero-thickness interface models are developed to describe the encapsulation of
microbubble contrast agents. Two different rheological models of the interface, Newtonian …

Response of contrast agents to ultrasound

V Sboros - Advanced drug delivery reviews, 2008 - Elsevier
Microbubbles are used as ultrasonic contrast agents that enhance the ultrasound signals of
the vascular bed. The recent development of site-targeted microbubbles opened up the …

Potential and problems in ultrasound-responsive drug delivery systems

YZ Zhao, LN Du, CT Lu, YG Jin… - International journal of …, 2013 - Taylor & Francis
Ultrasound is an important local stimulus for triggering drug release at the target tissue.
Ultrasound-responsive drug delivery systems (URDDS) have become an important research …

[HTML][HTML] Controlled Sonication as a Route to in-situ Graphene Flake Size Control

P Turner, M Hodnett, R Dorey, JD Carey - Scientific reports, 2019 - nature.com
Ultrasonication is widely used to exfoliate two dimensional (2D) van der Waals layered
materials such as graphene. Its fundamental mechanism, inertial cavitation, is poorly …