Lung cancer causes the highest mortality compared to other cancers in the world according
to the latest WHO reports. Non-small cell lung cancer (NSCLC) contributes about 85% of …

Ovarian cancer is a high-mortality malignancy in women. The contemporary clinical
chemotherapy with classic cytotoxic drugs, targeted molecular inhibitors would mostly fail …

Triple negative breast cancer (TNBC) with easy metastasis,“cold” tumor immune
microenvironment, and lack of targeted therapy remains poorly prognosed. Chemo …

Brain metastases are a most disturbing situation for breast cancer patients as there is
basically no adequate treatment available. Any potential drug formulation has to be able to …

The response of malignant glioma to immunotherapy remains gloomy due to its discrete
immunological environment and poor brain penetration of immunotherapeutic agents. Here …

Despite the exceptional progress in breast cancer pathogenesis, prognosis, diagnosis, and
treatment strategies, it remains a prominent cause of female mortality worldwide …

Arthritis is a kind of chronic disease that affects joints and muscles with the symptoms of joint
pain, inflammation and limited movement of joints. Among various clinical therapies, drug …

Tumor-targeted therapy based on nanoparticles is a popular research direction in the
biomedical field. After decades of research and development, both the passive targeting …

Cancer immunotherapy has revolutionized the standard of care for solid tumors in multiple
disease sites. In light of this, immune checkpoint blockade, directly interfering with various …

Poor water solubility and low bioavailability of active pharmaceutical ingredients (APIs) are
major causes of friction in the pharmaceutical industry and represent a formidable hurdle for …