The changing landscape of atherosclerosis

P Libby - Nature, 2021 - nature.com
Emerging evidence has spurred a considerable evolution of concepts relating to
atherosclerosis, and has called into question many previous notions. Here I review this …

[HTML][HTML] Epigenetic regulation in cardiovascular disease: mechanisms and advances in clinical trials

Y Shi, H Zhang, S Huang, L Yin, F Wang… - … and Targeted Therapy, 2022 - nature.com
Epigenetics is closely related to cardiovascular diseases. Genome-wide linkage and
association analyses and candidate gene approaches illustrate the multigenic complexity of …

Neutrophils as regulators of cardiovascular inflammation

C Silvestre-Roig, Q Braster, A Ortega-Gomez… - Nature Reviews …, 2020 - nature.com
Neutrophils have traditionally been viewed as bystanders or biomarkers of cardiovascular
disease. However, studies in the past decade have demonstrated the important functions of …

Insulin resistance and cardiovascular disease

CE Kosmas, MD Bousvarou… - Journal of …, 2023 - journals.sagepub.com
Insulin resistance (IR) and cardiovascular disease (CVD) represent two universal public
health hazards, especially in today's Western societies. A causal-effect relationship has …

[HTML][HTML] Therapeutic Potential of Natural Compounds Acting through Epigenetic Mechanisms in Cardiovascular Diseases: Current Findings and Future Directions

P Bontempo, L Capasso, L De Masi, A Nebbioso… - Nutrients, 2024 - mdpi.com
Cardiovascular diseases (CVDs) remain a leading global cause of morbidity and mortality.
These diseases have a multifaceted nature being influenced by a multitude of biochemical …

Incidence of transient ischemic attack and association with long-term risk of stroke

VA Lioutas, CS Ivan, JJ Himali, HJ Aparicio, T Leveille… - Jama, 2021 - jamanetwork.com
Importance Accurate estimation of the association between transient ischemic attack (TIA)
and risk of subsequent stroke can help to improve preventive efforts and limit the burden of …

[HTML][HTML] Pre-analytical factors that affect metabolite stability in human urine, plasma, and serum: a review

VL Stevens, E Hoover, Y Wang, KA Zanetti - Metabolites, 2019 - mdpi.com
Metabolomics provides a comprehensive assessment of numerous small molecules in
biological samples. As it integrates the effects of exogenous exposures, endogenous …

[HTML][HTML] Challenges in metabolomics-based tests, biomarkers revealed by metabolomic analysis, and the promise of the application of metabolomics in precision …

A Di Minno, M Gelzo, M Caterino, M Costanzo… - International Journal of …, 2022 - mdpi.com
Metabolomics helps identify metabolites to characterize/refine perturbations of biological
pathways in living organisms. Pre-analytical, analytical, and post-analytical limitations that …

[HTML][HTML] Digital healthcare: the future

CJT Butcher, W Hussain - Future healthcare journal, 2022 - Elsevier
Digital healthcare offers a huge range of possibilities and may improve the quality of patient
care. The traditional paradigm of clinical history, examination, differential diagnosis and …

[HTML][HTML] Prioritized research for the prevention, treatment, and reversal of chronic disease: recommendations from the lifestyle medicine research summit

Y Vodovotz, N Barnard, FB Hu, J Jakicic… - Frontiers in …, 2020 - frontiersin.org
Declining life expectancy and increasing all-cause mortality in the United States have been
associated with unhealthy behaviors, socioecological factors, and preventable disease. A …