Nonalcoholic fatty liver disease (NAFLD) and alcohol-related liver disease (ALD) are the
leading causes of chronic liver disease worldwide. NAFLD and ALD share …

Chronic liver disease (CLD) is a continuous process that causes a reduction of liver function
lasting more than six months. CLD includes alcoholic liver disease (ALD), non-alcoholic fatty …

Alcohol-associated liver disease (ALD) is a major cause of chronic liver disease worldwide,
and comprises a spectrum of several different disorders, including simple steatosis …

Background & Aims Binge drinking in patients with metabolic syndrome accelerates the
development of alcohol-associated liver disease. However, the underlying mechanisms …

The epidemic of obesity, type 2 diabetes and nonalcoholic liver disease (NAFLD) favors
drug consumption, which augments the risk of adverse events including liver injury. For …

Background: Alcohol-associated liver disease (ALD) is caused by chronic use of alcohol and
ranges from hepatic steatosis to fibrosis and cirrhosis. Bile acids are physiological …

A low-carbohydrate high-fat (LCHF) dietary pattern has been reported to improve chronic
metabolic diseases. However, whether and how the LCHF diet affects the pathological …

Type 2 diabetes mellitus (T2DM) represents one of the fastest growing epidemic metabolic
disorders worldwide and is a strong contributor for a broad range of comorbidities, including …

Sex is key variable influencing body composition and substrate utilization. At rest, females
maintain greater adiposity than males and resist the mobilization of fat. Males maintain …

Objective Hepatic steatosis is a key initiating event in the pathogenesis of alcohol-
associated liver disease (ALD), the most detrimental organ damage resulting from alcohol …