Scope This study aims to determine if previously developed physiologically‐based kinetic
(PBK) model in rat can be modified for senecionine (SEN) and its N‐oxide (SENO), and be …

Pyrrolizidine alkaloids (PAs) are produced by various plant species and have been detected
as contaminants in food and feed. Monitoring programmes should include PAs that are …

Ragworts like tansy ragwort (J. vulgaris Gaertn., syn. Senecio jacobaea L.) contain
hepatotoxic and cancerogenic pyrrolizidine alkaloids (PA) and their corresponding …

Pyrrolizidine alkaloids (PAs) are naturally occurring genotoxic compounds, and PA-
containing plants can pose a risk to humans through contaminated food sources and herbal …

This article presents the determination of eight pyrrolizidine alkaloids (PAs) by LC-MS/MS in
honeys, pollen, and Senecio brasiliensis (Asteraceae) samples, all from Santa Catarina …

Pyrrolizidine alkaloids (PAs) are natural toxins, supposed to be converted to hepatotoxic
metabolites in the liver of mammalians, and preventing the uptake of PAs is the only way to …

Honey samples originating from Australia were purchased and analysed for targeted
pyrrolizidine alkaloids (PAs) using a new and rapid isocratic LC-MS/MS method. This …

A risk ranking process identified Salmonella spp. and pathogenic verocytotoxin‐producing
Escherichia coli (VTEC) as current high‐priority biological hazards for meat inspection of …

Various studies have shown that honey may contain pyrrolizidine alkaloids (PAs) and thus
can pose a potential health risk for consumers. It seems that the level of contamination …

This study aimed to critically review methodologies for ranking of risks related to feed/food
safety and nutritional hazards, on the basis of their anticipated human health impact. An …