[HTML][HTML] Identification and causes of metabonomic difference between orthotopic and subcutaneous xenograft of pancreatic cancer

B Zhan, S Wen, J Lu, G Shen, X Lin, J Feng, H Huang - Oncotarget, 2017 - ncbi.nlm.nih.gov
Pancreatic ductal adenocarcinoma (PDAC) is one of the most lethal tumors. However, the
methodological differences between orthotopic and subcutaneous xenograft (OX and SX) …

Zebrafish reporter lines reveal in vivo signaling pathway activities involved in pancreatic cancer

M Schiavone, E Rampazzo, A Casari… - Disease models & …, 2014 - journals.biologists.com
Pancreatic adenocarcinoma, one of the worst malignancies of the exocrine pancreas, is a
solid tumor with increasing incidence and mortality in industrialized countries. This condition …

Expanding the spectrum of pancreatic cancers responsive to vesicular stomatitis virus-based oncolytic virotherapy: challenges and solutions

MC Holbrook, DW Goad, VZ Grdzelishvili - Cancers, 2021 - mdpi.com
Simple Summary Pancreatic ductal adenocarcinoma (PDAC) is a devastating malignancy
with a poor prognosis and a dismal survival rate. Oncolytic virus (OV) is an anticancer …

Heterodimeric RGD-NGR PET tracer for the early detection of pancreatic cancer

L Sun, Y Gai, Z Li, H Li, J Li, J Muschler, R Kang… - Molecular Imaging and …, 2022 - Springer
Purpose Pancreatic ductal adenocarcinoma (PDAC) is the most lethal gastrointestinal
cancer, and its poor prognosis is highly associated with the lack of an efficient early …

DNA polymerase theta plays a critical role in pancreatic cancer development and metastasis

A Smolinska, K Singer, J Golchert, U Smyczynska… - Cancers, 2022 - mdpi.com
Simple Summary Pancreatic ductal adenocarcinoma (PDAC) is one of the most deadly
cancers worldwide. The occurrence of oncogenic KRAS mutations is considered a signature …

Lipopolysaccharide‐induced hypothalamic inflammation in cancer cachexia‐anorexia is amplified by tumour‐derived prostaglandin E2

X Li, T Holtrop, FAC Jansen, B Olson… - Journal of cachexia …, 2022 - Wiley Online Library
Background Cachexia‐anorexia syndrome is a complex metabolic condition characterized
by skeletal muscle wasting, reduced food intake and prominent involvement of systemic and …

Identification of Ppy‐lineage cells as a novel origin of pancreatic ductal adenocarcinoma

OB Pereye, Y Nakagawa, T Sato… - The Journal of …, 2024 - Wiley Online Library
The Ppy gene encodes pancreatic polypeptide (PP) secreted by PP‐or γ‐cells, which are a
subtype of endocrine cells localised mainly in the islet periphery. For a detailed …

[HTML][HTML] Effects of salidroside on glioma formation and growth inhibition together with improvement of tumor microenvironment

Y Zhang, Y Yao, H Wang, Y Guo… - Chinese Journal of …, 2013 - ncbi.nlm.nih.gov
Objective To test the effects of salidroside on formation and growth of glioma together with
tumor microenvironment. Methods Salidroside extracted from Rhodiola rosea was purified …

TSPO-targeted PET and optical probes for the detection and localization of premalignant and malignant pancreatic lesions

AS Cohen, J Li, MR Hight, E McKinley, A Fu… - Clinical Cancer …, 2020 - AACR
Purpose: Pancreatic cancer is among the most aggressive malignancies and is rarely
discovered early. However, pancreatic “incidentalomas,” particularly cysts, are frequently …

[HTML][HTML] Constitutively active Akt1 cooperates with KRasG12D to accelerate in vivo pancreatic tumor onset and progression

TM Albury, V Pandey, SB Gitto, L Dominguez… - Neoplasia, 2015 - Elsevier
Abstract BACKGROUND AND AIMS: Pancreatic adenocarcinoma is a deadly disease
characterized by metastatic progression and resistance to conventional therapeutics …