Decellularized extracellular matrix: New promising and challenging biomaterials for regenerative medicine
Extracellular matrix is rich in biomolecules including structural proteins,
glycosaminoglycans, and small molecules that are important for the maintenance and repair …
glycosaminoglycans, and small molecules that are important for the maintenance and repair …
From shape to function: the next step in bioprinting
Abstract In 2013, the “biofabrication window” was introduced to reflect the processing
challenge for the fields of biofabrication and bioprinting. At that time, the lack of printable …
challenge for the fields of biofabrication and bioprinting. At that time, the lack of printable …
Recent advances in bioprinting techniques: approaches, applications and future prospects
J Li, M Chen, X Fan, H Zhou - Journal of translational medicine, 2016 - Springer
Bioprinting technology shows potential in tissue engineering for the fabrication of scaffolds,
cells, tissues and organs reproducibly and with high accuracy. Bioprinting technologies are …
cells, tissues and organs reproducibly and with high accuracy. Bioprinting technologies are …
Organoid-on-a-chip and body-on-a-chip systems for drug screening and disease modeling
Highlights•Traditional drug screening model systems are inadequate.•Organoid-on-a-chip
platforms stand to significantly advance drug and toxicology screening.•A wide variety or …
platforms stand to significantly advance drug and toxicology screening.•A wide variety or …
Liver organ-on-chip models for toxicity studies and risk assessment
T Messelmani, L Morisseau, Y Sakai, C Legallais… - Lab on a Chip, 2022 - pubs.rsc.org
The liver is a key organ that plays a pivotal role in metabolism and ensures a variety of
functions in the body, including homeostasis, synthesis of essential components, nutrient …
functions in the body, including homeostasis, synthesis of essential components, nutrient …
Recent advances in 2D and 3D in vitro systems using primary hepatocytes, alternative hepatocyte sources and non-parenchymal liver cells and their use in …
P Godoy, NJ Hewitt, U Albrecht, ME Andersen… - Archives of …, 2013 - Springer
This review encompasses the most important advances in liver functions and hepatotoxicity
and analyzes which mechanisms can be studied in vitro. In a complex architecture of nested …
and analyzes which mechanisms can be studied in vitro. In a complex architecture of nested …
[HTML][HTML] A multi-material bioink method for 3D printing tunable, cell-compatible hydrogels
3D bioprinting shows significant promise for creating complex tissue and organ mimics to
solve transplant needs and to provide platforms for drug testing and studying tissue …
solve transplant needs and to provide platforms for drug testing and studying tissue …
Designing decellularized extracellular matrix‐based bioinks for 3D bioprinting
A Abaci, M Guvendiren - Advanced healthcare materials, 2020 - Wiley Online Library
Abstract 3D bioprinting is an emerging technology to fabricate tissues and organs by
precisely positioning cells into 3D structures using printable cell‐laden formulations known …
precisely positioning cells into 3D structures using printable cell‐laden formulations known …
Extracellular matrix hydrogel therapies: In vivo applications and development
MT Spang, KL Christman - Acta biomaterialia, 2018 - Elsevier
Decellularized extracellular matrix (ECM) has been widely used for tissue engineering
applications and is becoming increasingly versatile as it can take many forms, including …
applications and is becoming increasingly versatile as it can take many forms, including …
Drug compound screening in single and integrated multi-organoid body-on-a-chip systems
Current practices in drug development have led to therapeutic compounds being approved
for widespread use in humans, only to be later withdrawn due to unanticipated toxicity …
for widespread use in humans, only to be later withdrawn due to unanticipated toxicity …