The chronic inflammatory bowel diseases (IBD), Crohn's disease and ulcerative colitis, are
recognized as important causes of gastrointestinal disease in children and adults. In this …

An increasing recognition has emerged of the complexities of the global health agenda—
specifically, the collision of infections and noncommunicable diseases and the dual burden …

The rapid accumulation of knowledge on apoptosis regulation in the 1990s was followed by
the development of several experimental anticancer‐and anti‐ischaemia (stroke or …

Aims Tumour necrosis factor-α (TNF-α) is a proinflammatory cytokine, which is implicated in
some metabolic disorders and may play a role in the development of cardiovascular …

1Department of Pathology and Microbiology, University of Bristol, Homoeopathic Hospital
Site, Cotham, Bristol BS6 6JU, UK; 2University of Glasgow Department of Surgery, Queen …

Tumour necrosis factor-α (TNF) expression is increased in inflammatory bowel disease
(IBD), and TNF maps to the IBD3 susceptibility locus. Transmission disequilibrium and case …

Tumour necrosis factor (TNF), an important proinflammatory cytokine, plays a role in the
regulation of cell differentiation, proliferation and death, as well as in inflammation, innate …

DNA repair is central to genomic integrity. Reduced expression of several nucleotide
excision repair genes has been demonstrated to be associated with increased risk of lung …

Stimulation of the NF-κB pathway often causes p65-p50 and p50-p50 dimers to be
simultaneously present in the cell nucleus. A natural polymorphism at nucleotide− 863 in the …

Inflammation plays an important role in the pathogenesis of atherosclerosis and acute
coronary syndromes. Cytokines IL-10 and TNF-α exert opposite functions in inflammatory …