Although vigorous immune responses are required to preserve a healthy state, a plethora of
undesired immune reactions can also occur, such as systemic autoimmunity, allograft …

We explored the immunoincompetence of mice undergoing a chronic graft-vs-host reaction
(GVHR) across minor histocompatibility barriers. BALB/c and B10. D2 mice are H-2d and …

A new method for measuring lymphocyte proliferation in response to mitogens and
allogeneic cells without using radiolabelling is described. It utilizes flow cytometry and the …

It was shown recently that a surface antigen termed TNKtar was likely to serve as a target
molecule for three distinct human NK clones expressing the same clonotypic determinant …

We have isolated and studied two alloreactive, T4+, human lymphocyte clones that release
interleukin 2 (IL-2) and interleukin 3 (IL-3) bioactivities upon stimulation with IL-2 …

The mixed lymphocyte culture procedure using tritiated thymidine (3H-TdR) incorporation is
time consuming and labor intensive, therefore costly. With the use of a fluorescent antibody …

The ability to effect selective regulation of the vigor of the immune response is a potential
therapeutic tool of great promise. Since transition of T cells from the quiescent to the active …

We have investigated if positive selection for cells expressing activation antigens, which
appear on the cell surface during T‐lymphocyte activation, could be used for cloning …

During my stint as a medical student and intern, nephrology was THE hot topic at Chicago's
University of Illinois College of Medicine in the 1960s, and I joined a rather large contingent …

The ability of highly purified resting human CD8 cells to respond to alloantigens in vitro was
examined. Necessary conditions for Induction of interleukin 2 receptors (IL‐2R), IL‐2 …