Engineering the next generation of cell-based therapeutics

CJ Bashor, IB Hilton, H Bandukwala… - Nature Reviews Drug …, 2022 - nature.com
Cell-based therapeutics are an emerging modality with the potential to treat many currently
intractable diseases through uniquely powerful modes of action. Despite notable recent …

Design of biodegradable, implantable devices towards clinical translation

C Li, C Guo, V Fitzpatrick, A Ibrahim… - Nature Reviews …, 2020 - nature.com
Biodegradable materials, including natural and synthetic polymers and hydrolyzable metals,
constitute the main components of temporary, implantable medical devices. Besides the …

Dealing with the foreign‐body response to implanted biomaterials: strategies and applications of new materials

D Zhang, Q Chen, C Shi, M Chen, K Ma… - Advanced Functional …, 2021 - Wiley Online Library
Foreign‐body response caused by implanted biomaterials seriously impedes the function of
implants and is a major obstacle to the development of implantable biomaterials and …

[HTML][HTML] Hyaluronic acid and chondroitin sulfate (meth) acrylate-based hydrogels for tissue engineering: Synthesis, characteristics and pre-clinical evaluation

CCL Schuurmans, M Mihajlovic, C Hiemstra, K Ito… - Biomaterials, 2021 - Elsevier
Hydrogels based on photocrosslinkable Hyaluronic Acid Methacrylate (HAMA) and
Chondroitin Sulfate Methacrylate (CSMA) are presently under investigation for tissue …

[HTML][HTML] Immunomodulatory bioactive glasses for tissue regeneration

K Zheng, W Niu, B Lei, AR Boccaccini - Acta Biomaterialia, 2021 - Elsevier
The regulatory functions of the immune response in tissue healing, repair, and regeneration
have been evidenced in the last decade. Immune cells play central roles in immune …

Advances in gelatin-based hydrogels for wound management

JI Kang, KM Park - Journal of Materials Chemistry B, 2021 - pubs.rsc.org
Skin wounds can be classified into two categories, namely acute and chronic wounds. While
acute wounds are healed by the normal wound healing process, chronic wounds are not …

[HTML][HTML] A review of biomimetic surface functionalization for bone-integrating orthopedic implants: Mechanisms, current approaches, and future directions

C Stewart, B Akhavan, SG Wise, MMM Bilek - Progress in Materials …, 2019 - Elsevier
Orthopedic implants are increasing in global prevalence, with hundreds of thousands of
operations performed annually. However, a significant proportion of these operations …

[HTML][HTML] Advances in biodegradable piezoelectrics for medical implants

T Liu, Y Wang, M Hong, J Venezuela, W Shi… - Nano Today, 2023 - Elsevier
Piezoelectric devices integrated into physiological systems can be used effectively for
biomedical applications such as sensing biological forces, self-powering biomedical …

[HTML][HTML] Additively manufactured pure zinc porous scaffolds for critical-sized bone defects of rabbit femur

D Xia, Y Qin, H Guo, P Wen, H Lin, M Voshage… - Bioactive materials, 2023 - Elsevier
Additive manufacturing has received attention for the fabrication of medical implants that
have customized and complicated structures. Biodegradable Zn metals are revolutionary …

Hydrogels in emerging technologies for type 1 diabetes

S Fuchs, AU Ernst, LH Wang, K Shariati… - Chemical …, 2020 - ACS Publications
Type 1 diabetes therapies that afford tighter glycemic control in a more manageable and
painless manner for patients has remained a central focus of next-generation diabetes …