Functional signatures of protective antiviral T‐cell immunity in human virus infections

A Harari, V Dutoit, C Cellerai, PA Bart… - Immunological …, 2006 - Wiley Online Library
The most common human viruses have different abilities to establish persistent chronic
infection. Virus‐specific T‐cell responses are critical in the control of virus replication and in …

Genetic susceptibility for breast cancer: how many more genes to be found?

RA Oldenburg, H Meijers-Heijboer… - Critical reviews in …, 2007 - Elsevier
Today, breast cancer is the most commonly occurring cancer among women. It accounts for
22% of all female cancers and the estimated annual incidence of breast cancer worldwide is …

Impaired NFAT nuclear translocation results in split exhaustion of virus-specific CD8+ T cell functions during chronic viral infection

P Agnellini, P Wolint, M Rehr… - Proceedings of the …, 2007 - National Acad Sciences
In persistent viral infections, the host's immune system is challenged by the constant
exposure to antigen, potentially causing continuous activation of CD8+ T cells with …

Association of human endogenous retroviruses with multiple sclerosis and possible interactions with herpes viruses

T Christensen - Reviews in medical virology, 2005 - Wiley Online Library
The hypothesis that human endogenous retroviruses (HERVs) play a role in autoimmune
diseases is subject to increasing attention. HERVs represent both putative susceptibility …

HERVs in neuropathogenesis

T Christensen - Journal of Neuroimmune Pharmacology, 2010 - Springer
In humans, exogenous retroviruses are known to cause immunodeficiency and neurological
disease. While endogenous retroviruses are firmly established pathogens in other species …

[HTML][HTML] Human T cell leukemia virus type I-induced disease: pathways to cancer and neurodegeneration

K Barmak, E Harhaj, C Grant, T Alefantis, B Wigdahl - Virology, 2003 - Elsevier
Retroviral infection is associated with a number of pathologic abnormalities, including a
variety of cancers, immunologic diseases, and neurologic disorders. Shortly after its …

Human T-Cell Lymphotropic Virus Type 1 p12I Expression Increases Cytoplasmic Calcium To Enhance the Activation of Nuclear Factor of Activated T Cells

W Ding, B Albrecht, RE Kelley, N Muthusamy… - Journal of …, 2002 - Am Soc Microbiol
Human T-cell lymphotropic virus type 1 (HTLV-1) establishes persistent infection and is
associated with lymphoproliferative or neurodegenerative diseases. As a complex retrovirus …

The past, present, and future of a human T-cell leukemia virus type 1 vaccine

JJ Tu, V Maksimova, L Ratner, AR Panfil - Frontiers in Microbiology, 2022 - frontiersin.org
Human T-cell leukemia virus type 1 (HTLV-1) is an oncogenic human retrovirus which
causes a lifelong infection. An estimated 5–10 million persons are infected with HTLV-1 …

Activation of Nuclear Factor of Activated T Cells by Human T-Lymphotropic Virus Type 1 Accessory Protein p12I

B Albrecht, CD D'Souza, W Ding… - Journal of …, 2002 - Am Soc Microbiol
Human T-lymphotropic virus type 1 (HTLV-1) is the agent of an aggressive malignancy of
CD4+ T lymphocytes, called adult T-cell lymphoma/leukemia, and is associated with …

Establishment of a novel human T-cell leukemia virus type 1 infection model using cell-free virus

K Nagata, K Tezuka, M Kuramitsu, N Fuchi… - Journal of …, 2024 - Am Soc Microbiol
The primary mode of infection by human T-cell leukemia virus type 1 (HTLV-1) is cell-to-cell
transmission during contact between infected cells and target cells. Cell-free HTLV-1 …