A review on chitosan and its development as pulmonary particulate anti-infective and anti-cancer drug carriers

RM Rasul, MT Muniandy, Z Zakaria, K Shah… - Carbohydrate …, 2020 - Elsevier
Chitosan, as a biodegradable and biocompatible polymer, is characterized by anti-microbial
and anti-cancer properties. It lately has received a widespread interest for use as the …

The confusing world of dry powder inhalers: it is all about inspiratory pressures, not inspiratory flow rates

AR Clark, JG Weers, R Dhand - Journal of aerosol medicine and …, 2020 - liebertpub.com
Dry powder inhalers (DPIs) all have the ability to aerosolize dry powders, but they each offer
different operating mechanisms and resistances to inhaled airflow. This variety has resulted …

[HTML][HTML] Inhalation treatment of primary lung cancer using liposomal curcumin dry powder inhalers

T Zhang, Y Chen, Y Ge, Y Hu, M Li, Y Jin - Acta Pharmaceutica Sinica B, 2018 - Elsevier
Lung cancer is the leading cause of cancer-related deaths. Traditional chemotherapy
causes serious toxicity due to the wide bodily distribution of these drugs. Curcumin is a …

Formulation strategies of nanosuspensions for various administration routes

SG Pınar, AN Oktay, AE Karaküçük, N Çelebi - Pharmaceutics, 2023 - mdpi.com
Nanosuspensions (NSs), which are nanosized colloidal particle systems, have recently
become one of the most interesting substances in nanopharmaceuticals. NSs have high …

[HTML][HTML] Influence of physical properties of carrier on the performance of dry powder inhalers

T Peng, S Lin, B Niu, X Wang, Y Huang, X Zhang… - … pharmaceutica sinica B, 2016 - Elsevier
Dry powder inhalers (DPIs) offer distinct advantages as a means of pulmonary drug delivery
and have attracted much attention in the field of pharmaceutical science. DPIs commonly …

Engineering the right formulation for enhanced drug delivery

WR Ke, RYK Chang, HK Chan - Advanced Drug Delivery Reviews, 2022 - Elsevier
Dry powder inhalers (DPIs) can be used with a wide range of drugs such as small molecules
and biologics and offer several advantages for inhaled therapy. Early DPI products were …

[HTML][HTML] Inhaled curcumin mesoporous polydopamine nanoparticles against radiation pneumonitis

T Chen, B Zhuang, Y Huang, Y Liu, B Yuan… - … Pharmaceutica Sinica B, 2022 - Elsevier
Radiation therapy is an effective method to kill cancer cells and shrink tumors using high-
energy X-ray or γ-ray. Radiation pneumonitis (RP) is one of the most serious complications …

A comprehensive overview of dry powder inhalers for pulmonary drug delivery: Challenges, advances, optimization techniques, and applications

HI Shahin, L Chablani - Journal of Drug Delivery Science and Technology, 2023 - Elsevier
Dry powder inhaler (DPI) is an attractive dosage form for local and systemic pulmonary drug
delivery. However, designing DPIs with adequate physicochemical properties is …

Designing inhaled protein therapeutics for topical lung delivery: what are the next steps?

E Bodier-Montagutelli, A Mayor, L Vecellio… - Expert opinion on …, 2018 - Taylor & Francis
Drug delivery in the airways by inhalation can be used for local and/or systemic action,
depending on the ability of the aerosolized drug to cross the air-blood barrier. For proteins …

The future of dry powder inhaled therapy: Promising or discouraging for systemic disorders?

Y Ye, Y Ma, J Zhu - International journal of pharmaceutics, 2022 - Elsevier
Dry powder inhalation therapy has been shown to be an effective method for treating
respiratory diseases like asthma, Chronic Obstructive Pulmonary Diseases and Cystic …