Neurogenesis persists during adulthood in the dentate gyrus of the hippocampus. Signals
provided by the local hippocampal microenvironment support neural stem cell proliferation …

Brain organoids are three-dimensional (3D) structures derived from human pluripotent stem
cells (hPSCs) that reflect early brain organization. These organoids contain different cell …

In this study, we have investigated the effects of Nano-curcumin (Nano-CUR) binding on
HSA-HTF interactions as binary and ternary systems, which had been done through multiple …

Alzheimer's Disease (AD) is the most common cause of dementia affecting the elderly
population worldwide. We have performed a comprehensive transcriptome profiling of Late …

Protein aggregation is classically considered the main cause of neuronal death in
neurodegenerative diseases (NDDs). However, increasing evidence suggests that alteration …

Alzheimer's disease (AD) is characterized by specific alterations of brain DNA methylation
(DNAm) patterns. Age and sex, two major risk factors for AD, are also known to largely affect …

Introduction Comparative transcriptome analyses in Alzheimer's disease (AD) and other
neurodegenerative proteinopathies can uncover both shared and distinct disease pathways …

Alzheimer's disease (AD) is one of the most common neurodegenerative diseases. Although
many researchers have attempted to explain the origins of AD, developing an effective …

Wnt pathway is involved in synaptic plasticity and neuronal survival, and alterations in Wnt
signaling have previously been reported both in aging and neurodegenerative diseases …

Importance Epigenetic modifications of the genome, such as DNA methylation and histone
modifications, have been reported to play a role in neurodegenerative diseases (ND) such …