[HTML][HTML] Bile acid nuclear receptor FXR and digestive system diseases

L Ding, L Yang, Z Wang, W Huang - Acta Pharmaceutica Sinica B, 2015 - Elsevier
Bile acids (BAs) are not only digestive surfactants but also important cell signaling
molecules, which stimulate several signaling pathways to regulate some important …

An update on the use and investigation of probiotics in health and disease

ME Sanders, F Guarner, R Guerrant, PR Holt… - Gut, 2013 - gut.bmj.com
Probiotics are derived from traditional fermented foods, from beneficial commensals or from
the environment. They act through diverse mechanisms affecting the composition or function …

Relevance of protein fermentation to gut health

K Windey, V De Preter… - Molecular nutrition & food …, 2012 - Wiley Online Library
It is generally accepted that carbohydrate fermentation results in beneficial effects for the
host because of the generation of short chain fatty acids, whereas protein fermentation is …

Obesity and colorectal cancer

M Bardou, AN Barkun, M Martel - Gut, 2013 - gut.bmj.com
Excess body weight, as defined by the body mass index (BMI), has been associated with
several diseases and includes subjects who are overweight (BMI≥ 25–29.9 kg/m2) or …

Diet and nutrient factors in colorectal cancer risk

AJ Vargas, PA Thompson - Nutrition in Clinical Practice, 2012 - Wiley Online Library
Diet and nutrition are estimated to explain as much as 30%–50% of the worldwide incidence
of colorectal cancer. In 2007, the World Cancer Research Fund (WCRF), in conjunction with …

Bile acids and colon cancer: Solving the puzzle with nuclear receptors

C Degirolamo, S Modica, G Palasciano… - Trends in molecular …, 2011 - cell.com
Colorectal cancer is the third most common malignancy worldwide and is often linked to
obesity, a sedentary lifestyle, carbohydrate-and fat-rich diets and elevated fecal excretion of …

High-protein diets for weight management: Interactions with the intestinal microbiota and consequences for gut health. A position paper by the my new gut study group

F Blachier, M Beaumont, KJ Portune, N Steuer, A Lan… - Clinical Nutrition, 2019 - Elsevier
Background & aims This review examines to what extent high-protein diets (HPD), which
may favor body weight loss and improve metabolic outcomes in overweight and obese …

A randomised crossover study investigating the effects of galacto-oligosaccharides on the faecal microbiota in men and women over 50 years of age

GE Walton, EGHM van den Heuvel… - British Journal of …, 2012 - cambridge.org
Faecal microbial changes associated with ageing include reduced bifidobacteria numbers.
These changes coincide with an increased risk of disease development. Prebiotics have …

The impact of pre‐and/or probiotics on human colonic metabolism: Does it affect human health?

V De Preter, HM Hamer, K Windey… - Molecular nutrition & …, 2011 - Wiley Online Library
Since many years, the role of the colonic microbiota in maintaining the host's overall health
and well‐being has been recognized. Dietary modulation of the microbiota composition and …

[图书][B] DNA damage, DNA repair and cancer

C Bernstein, AR Prasad, V Nfonsam, H Bernstein - 2013 - books.google.com
DNA damage appears to be a fundamental problem for life. In this chapter we review evi‐-
dence indicating that DNA damages are a major primary cause of cancer. DNA damages …