TGF-β family signaling in mesenchymal differentiation
I Grafe, S Alexander, JR Peterson… - Cold Spring …, 2018 - cshperspectives.cshlp.org
Mesenchymal stem cells (MSCs) can differentiate into several lineages during development
and also contribute to tissue homeostasis and regeneration, although the requirements for …
and also contribute to tissue homeostasis and regeneration, although the requirements for …
TGF-β signal transduction
J Massagué - Annual review of biochemistry, 1998 - annualreviews.org
The transforming growth factor β (TGF-β) family of growth factors control the development
and homeostasis of most tissues in metazoan organisms. Work over the past few years has …
and homeostasis of most tissues in metazoan organisms. Work over the past few years has …
Bone morphogenetic proteins: a critical review
B Bragdon, O Moseychuk, S Saldanha, D King… - Cellular signalling, 2011 - Elsevier
Bone Morphogenetic Proteins (BMPs) are potent growth factors belonging to the
Transforming Growth Factor Beta superfamily. To date over 20 members have been …
Transforming Growth Factor Beta superfamily. To date over 20 members have been …
Activins and inhibins: roles in development, physiology, and disease
M Namwanje, CW Brown - Cold Spring Harbor …, 2016 - cshperspectives.cshlp.org
Since their original discovery as regulators of follicle-stimulating hormone (FSH) secretion
and erythropoiesis, the TGF-β family members activin and inhibin have been shown to …
and erythropoiesis, the TGF-β family members activin and inhibin have been shown to …
Induction of apoptosis by ASK1, a mammalian MAPKKK that activates SAPK/JNK and p38 signaling pathways
Mitogen-activated protein (MAP) kinase cascades are activated in response to various
extracellular stimuli, including growth factors and environmental stresses. A MAP kinase …
extracellular stimuli, including growth factors and environmental stresses. A MAP kinase …
[PDF][PDF] The TGF-b superfamily: new members, new receptors, and new genetic tests of function in different organisms
D Kingsley - Genes and development, 1994 - scholar.archive.org
In the last 10 years, a large family of secreted signaling molecules has been discovered that
appear to mediate many key events in normal growth and development. The family is known …
appear to mediate many key events in normal growth and development. The family is known …
Mutations in the activin receptor–like kinase 1 gene in hereditary haemorrhagic telangiectasia type 2
DW Johnson, JN Berg, MA Baldwin, CJ Gallione… - Nature …, 1996 - nature.com
Hereditary haemorrhagic telangiectasia, or Osler–Rendu–Weber (ORW) syndrome, is an
autosomal dominant vascular dysplasia. So far, two loci have been demonstrated for ORW …
autosomal dominant vascular dysplasia. So far, two loci have been demonstrated for ORW …
Activin A in mammalian physiology
Activins are dimeric glycoproteins belonging to the transforming growth factor beta
superfamily and resulting from the assembly of two beta subunits, which may also be …
superfamily and resulting from the assembly of two beta subunits, which may also be …
The bone morphogenetic protein system in mammalian reproduction
S Shimasaki, RK Moore, F Otsuka… - Endocrine …, 2004 - academic.oup.com
Using molecular, cellular, and genetic approaches, recent studies examining the role of the
bone morphogenetic protein (BMP) family of growth factors in the reproductive system have …
bone morphogenetic protein (BMP) family of growth factors in the reproductive system have …
Activin receptor-like kinase 1 modulates transforming growth factor-β1 signaling in the regulation of angiogenesis
The activin receptor-like kinase 1 (ALK1) is a type I receptor for transforming growth factor-β
(TGF-β) family proteins. Expression of ALK1 in blood vessels and mutations of the ALK1 …
(TGF-β) family proteins. Expression of ALK1 in blood vessels and mutations of the ALK1 …