Malaria, a mosquito-borne infection, is the most widespread parasitic disease. Despite
numerous efforts to eradicate malaria, this disease is still a health concern worldwide. Owing …

Genetic variability in Plasmodium falciparum malaria parasites hampers current malaria
vaccine development efforts. Here, we hypothesize that to address the impact of genetic …

Remarkable progress has been made in coordinated malaria control efforts with substantial
reductions in malaria-associated deaths and morbidity achieved through mass …

The malaria parasite Plasmodium falciparum proliferates in the blood stream where the host
immune system is most active. To escape from host immunity, P. falciparum has developed a …

Serine repeat antigen (SERA) is conserved among species of the genus Plasmodium. Sera
genes form a multigene family and are generally tandemly clustered on a single …

The call for second generation malaria vaccines needs not only the identification of novel
candidate antigens or adjuvants but also a better understanding of immune responses and …

Malaria is a deadly disease that takes the lives of more than 420,000 people a year and is
responsible for more than 229 million clinical cases globally. In 2019, 95% of malaria …

Introduction: An efficacious malaria vaccine is necessary to advance the current control
measures towards malaria elimination. To-date, only RTS, S/AS01, a leading pre …

Plasmodium falciparum Cysteine-Rich Protective Antigen (CyRPA) is an essential, highly
conserved merozoite antigen that forms an important multi-protein complex …

Background The pathogenesis of malaria is primarily associated with blood-stage infection
and there is strong evidence that antibodies specific for parasite blood-stage antigens can …