[HTML][HTML] The N-Terminal Region of Plasmodium falciparum MSP10 Is a Target of Protective Antibodies in Malaria and Is Important for PfGAMA/PfMSP10 Interaction

H Nagaoka, BN Kanoi, K Jinoka, M Morita… - Frontiers in …, 2019 - frontiersin.org
Clinical manifestation of malaria is mainly due to intra-erythrocytic development of
Plasmodium parasites. Plasmodium falciparum merozoites, the invasive form of the blood …

[HTML][HTML] Malaria vaccine approaches leveraging technologies optimized in the COVID-19 era

BN Kanoi, M Maina, C Likhovole, FM Kobia… - Frontiers in Tropical …, 2022 - frontiersin.org
Africa bears the greatest burden of malaria with more than 200 million clinical cases and
more than 600,000 deaths in 2020 alone. While malaria-associated deaths dropped steadily …

[HTML][HTML] Meta-Analysis of Human Antibodies Against Plasmodium falciparum Variable Surface and Merozoite Stage Antigens

E Takashima, BN Kanoi, H Nagaoka, M Morita… - Frontiers in …, 2022 - frontiersin.org
Concerted efforts to fight malaria have caused significant reductions in global malaria cases
and mortality. Sustaining this will be critical to avoid rebound and outbreaks of seasonal …

[HTML][HTML] Potential and limitations of cross-protective vaccine against malaria by blood-stage naturally attenuated parasite

T Imai, K Suzue, H Ngo-Thanh, C Shimokawa… - Vaccines, 2020 - mdpi.com
Human malaria vaccine trials have revealed vaccine efficacy but improvement is still
needed. In this study, we aimed to re-evaluate vaccination with blood-stage naturally …

[HTML][HTML] Hematological and biochemical data obtained in rural Northern Uganda

NMQ Palacpac, E Ntege, B Balikagala, A Yeka… - International Journal of …, 2014 - mdpi.com
Reference intervals for common hematological and clinical chemistry parameters constitute
an important basis for health care. Moreover, with increasing priority in drug and vaccine …

Infectious plasmodium sporozoites grown in vitro

AG Eappen, SL Hoffman - US Patent 9,878,026, 2018 - Google Patents
The application is directed to in-vitro-reared Plasmodium sporozoites of human host range
wherein sporogony from gametocyte stage to sporozoite stage is external to mosquitoes …

Preclinical studies on a new vaccine formulation of BK-SE36, a malaria vaccine candidate

NMQ PALACPAC, T TOUGAN, T HORII - Juntendo Medical Journal, 2015 - jstage.jst.go.jp
An effective blood-stage vaccine remains elusive but necessary if we are to reduce malaria
morbidity and mortality. The SE36 antigen derived from serine repeat antigen 5 (SERA5) of …

Avances en el desarrollo de una vacuna contra la malaria por Plasmodium falciparum: una revisión de literatura

AMG Rodríguez… - Revista …, 2020 - revistasdigitales.uniboyaca.edu.co
Introducción. La malaria por Plasmodium falciparum es una enfermedad causante de altas
tasas de morbimortalidad a nivel mundial. Diferentes candidatos a vacuna se han evaluado …

[HTML][HTML] Identifying Merozoite Targets of Protective Immunity Against Plasmodium falciparum Malaria

G Kamuyu - 2017 - oro.open.ac.uk
The observation that individuals living in malaria endemic regions who are repeatedly
infected with P. falciparum can acquire immunity, first to severe, then to uncomplicated …

Anti-parasitic antibodies from phage display

LR Goulart, V da S. Ribeiro, JM Costa-Cruz - Recombinant Antibodies for …, 2017 - Springer
Parasite infections affect billions of people and their domesticated animals worldwide, and
remain as a significant cause of morbidity and mortality, but such diseases are still neglected …