Spin hyperpolarization in modern magnetic resonance

J Eills, D Budker, S Cavagnero, EY Chekmenev… - Chemical …, 2023 - ACS Publications
Magnetic resonance techniques are successfully utilized in a broad range of scientific
disciplines and in various practical applications, with medical magnetic resonance imaging …

[HTML][HTML] Dynamic nuclear polarization for sensitivity enhancement in modern solid-state NMR

ASL Thankamony, JJ Wittmann, M Kaushik… - Progress in nuclear …, 2017 - Elsevier
The field of dynamic nuclear polarization has undergone tremendous developments and
diversification since its inception more than 6 decades ago. In this review we provide an in …

[HTML][HTML] Solid-state NMR spectroscopy in pharmaceutical sciences

M Li, W Xu, Y Su - TrAC Trends in Analytical Chemistry, 2021 - Elsevier
Solid-state NMR (ssNMR) spectroscopy analyzes a wide range of pharmaceutical materials
in a non-disruptive and non-invasive manner. The obtained molecular properties at …

Recent developments in MAS DNP-NMR of materials

AGM Rankin, J Trébosc, F Pourpoint… - Solid State Nuclear …, 2019 - Elsevier
Solid-state NMR spectroscopy is a powerful technique for the characterization of the atomic-
level structure and dynamics of materials. Nevertheless, the use of this technique is often …

Hyperpolarized water as universal sensitivity booster in biomolecular NMR

C Hilty, D Kurzbach, L Frydman - Nature protocols, 2022 - nature.com
NMR spectroscopy is the only method to access the structural dynamics of biomolecules at
high (atomistic) resolution in their native solution state. However, this method's low …

Pharmaceutical cocrystals, salts and polymorphs: Advanced characterization techniques

E Pindelska, A Sokal, W Kolodziejski - Advanced drug delivery reviews, 2017 - Elsevier
The main goal of a novel drug development is to obtain it with optimal physiochemical,
pharmaceutical and biological properties. Pharmaceutical companies and scientists modify …

Pharmaceutical hydrates analysis—overview of methods and recent advances

E Jurczak, AH Mazurek, Ł Szeleszczuk, DM Pisklak… - Pharmaceutics, 2020 - mdpi.com
This review discusses a set of instrumental and computational methods that are used to
characterize hydrated forms of APIs (active pharmaceutical ingredients). The focus has been …

Transportable hyperpolarized metabolites

X Ji, A Bornet, B Vuichoud, J Milani, D Gajan… - Nature …, 2017 - nature.com
Nuclear spin hyperpolarization of 13C-labelled metabolites by dissolution dynamic nuclear
polarization can enhance the NMR signals of metabolites by several orders of magnitude …

Measuring nano-to microstructures from relayed dynamic nuclear polarization NMR

AC Pinon, J Schlagnitweit, P Berruyer… - The Journal of …, 2017 - ACS Publications
We show how dynamic nuclear polarization (DNP) NMR can be used in combination with
models for polarization dynamics to determine the domain sizes in complex materials. By …

Understanding surface and interfacial chemistry in functional nanomaterials via solid‐state NMR

A Marchetti, J Chen, Z Pang, S Li, D Ling… - Advanced …, 2017 - Wiley Online Library
Surface and interfacial chemistry is of fundamental importance in functional nanomaterials
applied in catalysis, energy storage and conversion, medicine, and other nanotechnologies …