The sirtuin family in health and disease
QJ Wu, TN Zhang, HH Chen, XF Yu, JL Lv… - … and Targeted Therapy, 2022 - nature.com
Sirtuins (SIRTs) are nicotine adenine dinucleotide (+)-dependent histone deacetylases
regulating critical signaling pathways in prokaryotes and eukaryotes, and are involved in …
regulating critical signaling pathways in prokaryotes and eukaryotes, and are involved in …
The role of BCL-2 family proteins in regulating apoptosis and cancer therapy
S Qian, Z Wei, W Yang, J Huang, Y Yang… - Frontiers in …, 2022 - frontiersin.org
Apoptosis, as a very important biological process, is a response to developmental cues or
cellular stress. Impaired apoptosis plays a central role in the development of cancer and …
cellular stress. Impaired apoptosis plays a central role in the development of cancer and …
Overcoming barriers in photodynamic therapy harnessing nano-formulation strategies
Photodynamic therapy (PDT) has been extensively investigated for decades for tumor
treatment because of its non-invasiveness, spatiotemporal selectivity, lower side-effects, and …
treatment because of its non-invasiveness, spatiotemporal selectivity, lower side-effects, and …
The apoptosis paradox in cancer
O Morana, W Wood, CD Gregory - International journal of molecular …, 2022 - mdpi.com
Cancer growth represents a dysregulated imbalance between cell gain and cell loss, where
the rate of proliferating mutant tumour cells exceeds the rate of those that die. Apoptosis, the …
the rate of proliferating mutant tumour cells exceeds the rate of those that die. Apoptosis, the …
Targeting ferroptosis in acute kidney injury
L Ni, C Yuan, X Wu - Cell Death & Disease, 2022 - nature.com
Acute kidney injury (AKI) is a major public health problem with high incidence and mortality.
As a form of programmed cell death (PCD), ferroptosis could be considered as a process of …
As a form of programmed cell death (PCD), ferroptosis could be considered as a process of …
Mitochondrial dynamics: overview of molecular mechanisms
L Tilokani, S Nagashima, V Paupe… - Essays in …, 2018 - portlandpress.com
Mitochondria are highly dynamic organelles undergoing coordinated cycles of fission and
fusion, referred as 'mitochondrial dynamics', in order to maintain their shape, distribution and …
fusion, referred as 'mitochondrial dynamics', in order to maintain their shape, distribution and …
Endoplasmic reticulum stress-mediated autophagy activation is involved in cadmium-induced ferroptosis of renal tubular epithelial cells
C Zhao, D Yu, Z He, L Bao, L Feng, L Chen… - Free Radical Biology …, 2021 - Elsevier
Acute cadmium (Cd) exposure is a significant risk factor for renal injury and lacks effective
treatment strategies. Ferroptosis is a recently identified iron-dependent form of nonapoptotic …
treatment strategies. Ferroptosis is a recently identified iron-dependent form of nonapoptotic …
[HTML][HTML] Understanding apoptosis and apoptotic pathways targeted cancer therapeutics
R Jan - Advanced pharmaceutical bulletin, 2019 - ncbi.nlm.nih.gov
Various physiological processes involve appropriate tissue developmental process and
homeostasis-the pathogenesis of several diseases connected with deregulatory apoptosis …
homeostasis-the pathogenesis of several diseases connected with deregulatory apoptosis …
Neuronal cell death
M Fricker, AM Tolkovsky, V Borutaite… - Physiological …, 2018 - journals.physiology.org
Neuronal cell death occurs extensively during development and pathology, where it is
especially important because of the limited capacity of adult neurons to proliferate or be …
especially important because of the limited capacity of adult neurons to proliferate or be …
Cell death mediated by the pyroptosis pathway with the aid of nanotechnology: prospects for cancer therapy
Pyroptosis, a unique form of programmed cell death (PCD) that is characterized by DNA
fragmentation, chromatin condensation, cellular swelling with big bubbles, and leakage of …
fragmentation, chromatin condensation, cellular swelling with big bubbles, and leakage of …