The feasibility of artificial consciousness through the lens of neuroscience

J Aru, ME Larkum, JM Shine - Trends in Neurosciences, 2023 - cell.com
Interactions with large language models (LLMs) have led to the suggestion that these
models may soon be conscious. From the perspective of neuroscience, this position is …

[HTML][HTML] Brain-heart interactions in the neurobiology of consciousness

D Candia-Rivera - Current Research in Neurobiology, 2022 - Elsevier
Recent experimental evidence on patients with disorders of consciousness revealed that
observing brain-heart interactions helps to detect residual consciousness, even in patients …

Thalamic deep brain stimulation in traumatic brain injury: a phase 1, randomized feasibility study

ND Schiff, JT Giacino, CR Butson, EY Choi, JL Baker… - Nature Medicine, 2023 - nature.com
Converging evidence indicates that impairments in executive function and information-
processing speed limit quality of life and social reentry after moderate-to-severe traumatic …

[PDF][PDF] The non-specific matrix thalamus facilitates the cortical information processing modes relevant for conscious awareness

EJ Müller, BR Munn, MJ Redinbaugh, J Lizier… - Cell Reports, 2023 - cell.com
The neurobiological mechanisms of arousal and anesthesia remain poorly understood.
Recent evidence highlights the key role of interactions between the cerebral cortex and the …

A thalamocortical substrate for integrated information via critical synchronous bursting

BR Munn, EJ Müller, J Aru, CJ Whyte… - Proceedings of the …, 2023 - National Acad Sciences
Understanding the neurobiological mechanisms underlying consciousness remains a
significant challenge. Recent evidence suggests that the coupling between distal–apical …

In vivo mapping of pharmacologically induced functional reorganization onto the human brain's neurotransmitter landscape

AI Luppi, JY Hansen, R Adapa, RL Carhart-Harris… - Science …, 2023 - science.org
To understand how pharmacological interventions can exert their powerful effects on brain
function, we need to understand how they engage the brain's rich neurotransmitter …

Prefrontal cortex as a key node in arousal circuitry

GA Mashour, D Pal, EN Brown - Trends in neurosciences, 2022 - cell.com
The role of the prefrontal cortex (PFC) in the mechanism of consciousness is a matter of
active debate. Most theoretical and empirical investigations have focused on whether the …

Local orchestration of distributed functional patterns supporting loss and restoration of consciousness in the primate brain

AI Luppi, L Uhrig, J Tasserie, CM Signorelli… - Nature …, 2024 - nature.com
A central challenge of neuroscience is to elucidate how brain function supports
consciousness. Here, we combine the specificity of focal deep brain stimulation with fMRI …

[HTML][HTML] Decreased thalamic activity is a correlate for disconnectedness during anesthesia with propofol, dexmedetomidine and sevoflurane but not S-ketamine

O Kantonen, L Laaksonen, M Alkire… - Journal of …, 2023 - Soc Neuroscience
Establishing the neural mechanisms responsible for the altered global states of
consciousness during anesthesia and dissociating these from other drug-related effects …

A synergistic workspace for human consciousness revealed by integrated information decomposition

AI Luppi, PAM Mediano, FE Rosas, J Allanson… - BioRxiv, 2020 - biorxiv.org
A central goal of neuroscience is to understand how the brain synthesises information from
multiple inputs to give rise to a unified conscious experience. This process is widely …