Angiogenesis is critical in tissue engineering, and bioceramic-induced angiogenesis has
been reported. However, the role of other types of cells such as fibroblasts in this bioceramic …

Vascular endothelial growth factors (VEGFs) regulate blood and lymphatic vessel
development and homeostasis but also have profound effects on neural cells. VEGFs are …

After surgical resection for a bone tumor, the uncleared bone tumor cells can multiply and
cause recurrence of the bone tumor. It is worthwhile to design a scaffold that kills the …

Endothelium forms a semi-permeable barrier that separates blood from the underlying
tissue. Barrier function is largely determined by cell-cell and cell-matrix adhesions that …

Cell-penetrating peptides, CPPs, have been shown to translocate into living cells by a
receptor-independent mechanism and to carry macromolecules over the plasma membrane …

Natural inhibitors of angiogenesis are able to block pathological neovascularization without
harming the preexisting vasculature. Here we show that two such inhibitors, thrombospondin …

In several pathological conditions, epithelial cells demonstrate a breakdown of barrier
function and acquire an invasive phenotype. Endothelial cells in particular are maintained in …

In order for cancer cells to successfully colonize a metastatic site, they must detach from the
primary tumor using extracellular matrix-degrading proteases, intravasate and survive in the …

Blood-flow interactions with the vascular endothelium represents a specialized example of
mechanical regulation of cell function that has important physiological and …

It is presently accepted that fibroblast/myofibroblast modulation represents a crucial step in
granulation tissue contraction and in the production of the connective tissue deformations …