Vascular endothelial cadherin (VE-cadherin) is an endothelial cell–specific cadherin that
plays an important role in the control of vascular organization. Blocking VE-cadherin …

Using the Cre/loxP system we conditionally inactivated β-catenin in endothelial cells. We
found that early phases of vasculogenesis and angiogenesis were not affected in mutant …

Diabetic retinopathy (DR) remains a major complication of diabetes and a leading cause of
blindness among adults worldwide. DR is a progressive disease affecting both type I and …

Glucocorticoids (GCs) are steroid hormones that have inflammatory and
immunosuppressive effects on a wide variety of cells. They are used as therapy for …

The integrity of the endothelium is dependent on cell-cell adhesion, which is mediated by
vascular-endothelial (VE)-cadherin. Proper VE-cadherin-mediated homotypic adhesion is, in …

The permeability of exchange microvessels is regulated through complex interactions
between signaling molecules and structural proteins in the endothelium. Endothelial barrier …

OBJECTIVE—Increased vascular permeability due to alteration of the blood-retinal barrier
(BRB) is one of the major complications in early diabetes. The aim of the present study was …

Vascular endothelial growth factor (VEGF), also known as vascular permeability factor
(VPF), has been shown to increase potently the permeability of endothelium and is highly …

Recent work from several laboratories indicates that the coordination of endothelial cell
adhesion events with growth factor receptor inputs regulates endothelial cell responses …

Vascular hyperpermeability, the excessive leakage of fluid and proteins from blood vessels
to the interstitial space, commonly occurs in traumatic and ischemic injuries. This …