Previously published reports support the concept that, besides promoting homotypic
intercellular adhesion, cadherins may transfer intracellular signals. However, the signaling …

Leukocyte adhesion is mediated totally and transendothelial migration partially by
heterotypic interactions between the β1-and β2-integrins on the leukocytes and their …

The formation of matrix-rich, vasculogenic-like networks, termed vasculogenic mimicry (VM),
is a unique process characteristic of highly aggressive melanoma cells found to express …

VE-cadherin was first identified in the early 1990s and quickly emerged as an important
endothelial cell adhesion molecule. The past decade of research has revealed key roles for …

Changes in vascular endothelial (VE)-cadherin–mediated cell-cell adhesion and integrin-
mediated cell-matrix adhesion coordinate to affect the physical and mechanical …

An important function of the endothelium is to regulate the transport of liquid and solutes
across the semi-permeable vascular endothelial barrier. Two cellular pathways controlling …

Diabetic macular oedema (DMO) is an important cause of vision loss in patients with
diabetes mellitus. The underlying mechanisms of DMO, on both macrocellular and …

Molecular mechanisms controlling arterial–venous specification have not been fully
elucidated. Previously, we established an embryonic stem cell differentiation system and …

This review provides the theoretical background of phenotypic and gene-based changes in
the vessel wall triggered by acute hypoxia. Only in the last few decades has the endothelium …

It has been suggested that increasing levels of shear stress could modify endothelial
permeability. This might be critical in venous grafting and in the pathogenesis of certain …